Exosomes derived from umbilical cord mesenchymal stem cells reduce microglia-mediated neuroinflammation in perinatal brain injury

被引:0
作者
Gierin Thomi
Daniel Surbek
Valérie Haesler
Marianne Joerger-Messerli
Andreina Schoeberlein
机构
[1] Inselspital,Department of Obstetrics and Feto
[2] Bern University Hospital,maternal Medicine, University Women’s Hospital
[3] University of Bern,Department for BioMedical Research (DBMR)
[4] University of Bern,Graduate School for Cellular and Biomedical Sciences
来源
Stem Cell Research & Therapy | / 10卷
关键词
Preterm birth; Perinatal brain damage; White matter injury; Neuroinflammation; Hypoxia-ischemia; Mesenchymal stem cells; Umbilical cord; Extracellular vesicles; Exosomes; Intranasal; Microglia; BV-2;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 258 条
[1]  
Goldenberg RL(2008)Epidemiology and causes of preterm birth Lancet. 371 75-84
[2]  
Culhane JF(2015)Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012 JAMA. 314 1039-1051
[3]  
Iams JD(2011)Population based age stratified morbidities of premature infants in Switzerland Swiss Med Wkly 141 w13212-58
[4]  
Romero R(2008)Cognitive and educational deficits in children born extremely preterm Semin Perinatol 32 51-63.e1
[5]  
Stoll BJ(2012)Neurological and developmental outcome in extremely preterm children born in England in 1995 and 2006: the EPICure studies BMJ. 345 e7961-346
[6]  
Hansen NI(2010)Psychiatric disorders in extremely preterm children: longitudinal finding at age 11 years in the EPICure study J Am Acad Child Adolesc Psychiatry 49 453-20
[7]  
Bell EF(2014)Neurobiology of premature brain injury Nat Neurosci 17 341-823
[8]  
Walsh MC(2012)Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases Brain Res Bull 87 10-208
[9]  
Carlo WA(2017)Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats Stem Cell Res Ther 8 198-1242
[10]  
Shankaran S(2017)Mesenchymal stem cell-derived microvesicles modulate lipopolysaccharides-induced inflammatory responses to microglia cells Stem Cells 35 812-1049