Registry on assessing the quality of life improvement with triamcinolone in the treatment of moderate-to-severe persistent allergic rhinitis in egyptian patients

Abstract Background: Allergic rhinitis is a common disorder that can significantly impact the quality of life of patient. It is strongly linked to asthma and conjunctivitis. The classic symptoms of the disorder are nasal congestion and itching, rhinorrhea, and sneezing. Currently, steroids have played a role in the management of allergic rhinitis. The aim of the study was to assess the efficacy and safety of triamcinolone in the treatment of allergic rhinitis in Egypt. Patients and methods: A total of 308 Egyptian patients who were suffering from moderate-to-severe allergic rhinitis and were prescribed triamcinolone were enrolled. The improvement in the quality of life of patients receiving triamcinolone after 4 weeks of treatment was assessed using the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). All adverse events were recorded during the study duration. Results: The RQLQ showed a significant improvement in the quality of life of patients after using triamcinolone. The mean RQLQ score before triamcinolone administration was 2.99±1.015 versus 0.68±0.706 after 4 weeks of treatment (P<0.001), with a mean percent reduction of −76.78±23.62%. The individual domain scores of the RQLQ after 4 weeks of treatment showed a significant improvement in the level of all domains. No adverse events were reported and the drug showed a high tolerability profile. Conclusion: Triamcinolone is considered an efficient and safe drug in the management of allergic rhinitis. It has a positive impact on the quality of life of patients with moderate-to-severe persistent allergic rhinitis under conditions of daily practice in patients receiving triamcinolone after 4 weeks of treatment. © 2016, The Author(s).