Human U87 glioblastoma cells with stemness features display enhanced sensitivity to natural killer cell cytotoxicity through altered expression of NKG2D ligand

被引:0
作者
Se-Jeong Oh
Jung-In Yang
Ok Kim
Eun-Jung Ahn
Woo Dae Kang
Jae-Hyuk Lee
Kyung-Sub Moon
Kyung-Hwa Lee
Duck Cho
机构
[1] Chonnam National University Hwasun Hospital and Medical School,Department of Neurosurgery
[2] Chonnam National University Hwasun Hospital and Medical School,Department of Pathology
[3] Chonnam National University Hwasun Hospital and Medical School,Department of Obstetrics and Gynecology
[4] Sungkyunkwan University School of Medicine,Department of Laboratory Medicine and Genetics, Samsung Medical Center
来源
Cancer Cell International | / 17卷
关键词
Cancer stem cells; Glioblastoma; Immunotherapy; Natural killer cell; U87;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 173 条
  • [1] Ostrom QT(2014)The epidemiology of glioma in adults: a “state of the science” review Neuro Oncol. 16 896-913
  • [2] Bauchet L(2016)Glioma stem cells: signaling, microenvironment, and therapy Stem Cells Int. 2016 7849890-5
  • [3] Davis FG(2011)NK cell-based immunotherapy for treating cancer: will it be promising? Korean J Hematol. 46 3-4017
  • [4] Deltour I(2009)Expansion of highly cytotoxic human natural killer cells for cancer cell therapy Cancer Res 69 4010-174
  • [5] Fisher JL(2012)Human glioblastoma stem-like cells are more sensitive to allogeneic NK and T cell-mediated killing compared with serum-cultured glioblastoma cells Brain Pathol 22 159-3539
  • [6] Langer CE(2009)NK cells recognize and kill human glioblastoma cells with stem cell-like properties J Immunol. 182 3530-3909
  • [7] Pekmezci M(2010)Cytotoxicity of activated natural killer cells against pediatric solid tumors Clin Cancer Res 16 3901-383
  • [8] Schwartzbaum JA(2005)Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells Blood 106 376-2533
  • [9] Turner MC(2013)Immunological characterization of glioblastoma cells for immunotherapy Anticancer Res 33 2525-106
  • [10] Walsh KM(2016)Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line J Neurol Sci 367 101-4844