A highly sensitive sensor of paracetamol based on zinc-layered hydroxide-L-phenylalanate-modified multiwalled carbon nanotube paste electrode

被引：0
作者：
Mohamad Syahrizal Ahmad
Illyas Md Isa
Norhayati Hashim
Suyanta M. Si
Mohamad Idris Saidin
机构：
[1] Sultan Idris Education University,Nanotechnology Research Centre, Faculty of Science and Mathematics
[2] Sultan Idris Education University,Department of Chemistry, Faculty of Science and Mathematics
[3] Yogyakarta State University,Department of Chemistry Education, Faculty of Mathematics and Natural Science
[4] MIMOS Bhd.,Advanced Analytical Services Laboratory
[5] Technology Park of Malaysia,undefined
来源：
Journal of Solid State Electrochemistry | 2018年 / 22卷
关键词：
Paracetamol; Multiwalled carbon nanotubes; Square wave voltammetry; Chronocoulometry; Zinc layered hydroxide-; -phenylalanate;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new zinc-layered hydroxide-L-phenylalanate (ZLH-LP)-modified multiwalled carbon nanotube (MWCNT) was prepared as a new material of paste electrode for the detection of paracetamol (PCM) in 1.0 × 10−1 M phosphate buffer solution and at pH 7.5. The electrochemical characterization of the MWCNTs/ZLH-LP paste electrode was characterized by square wave voltammetry, electrochemical impedance spectroscopy, and cyclic voltammetry while the morphology properties of the MWCNTs, ZLH-LP, and MWCNTs/ZLH-LP were investigated using transmission electron microscopy and scanning electron microscopy. Under optimized conditions, the MWCNTs/ZLH-LP paste electrode demonstrated an excellent electrocatalytic activity towards oxidation of PCM in the linear responses’ ranges from 7.0 × 10−7 M to 1.0 × 10−4 M (correlation coefficient, 0.996) with the limit of detection obtained at 8.3 × 10−8 M. As a conclusion, the MWCNTs/ZLH-LP paste electrode revealed good repeatability, reproducibility, and stability, and was found to be applicable for use in pharmaceutical tablet samples.
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页码：2691 / 2701
页数：10
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