Acute viral hepatitis

被引:0
作者
Gerlach J.T. [1 ,2 ]
Müllhaupt B. [1 ]
机构
[1] Klinik für Gastroenterologie und Hepatologie, Zürich
[2] Klinik für Gastroenterologie und Hepatologie, 8091 Zürich
来源
Der Gastroenterologe | 2007年 / 2卷 / 3期
关键词
Acute viral hepatitis; Fulminant; Icteric; Seroconversion;
D O I
10.1007/s11377-007-0085-6
中图分类号
学科分类号
摘要
Viral hepatitis belongs to the most common infectious diseases worldwide. While the diagnosis of acute hepatitis A, B and E is based on specific IgM-antibodies, diagnosis of acute hepatitis C is difficult and requires serologic follow-up. Viral hepatitis presents with non-specific prodromi of fatigue, myalgia and arthralgia followed by jaundice and right upper quadrant pain. While acute hepatitis A is inapparent in childhood, the majority of adults develop icteric hepatitis. Acute hepatitis A infection is cleared completely. In western countries hepatitis B is commonly transmitted parenterally and sexually, and acute hepatitis is eliminated spontaneously in 95% of acute infections. Icteric acute hepatitis B is found in 25% of cases and fulminant liver failure develops in less than 1%. Today, hepatitis C is transmitted mainly by iv-drug abuse and causes chronic hepatitis in 60-80% of infections. Acute HCV infection is rarely diagnosed since it is commonly asymptomatic. © Springer Medizin Verlag 2007.
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页码:186 / 193
页数:7
相关论文
共 26 条
[1]  
Siegl G., Weitz M., Kronauer G., Stability of Hepatitis A virus, Intervirology, 22, pp. 218-226, (1984)
[2]  
Feinstone S.M., Kapikian A.Z., Purceli R.H., Hepatitis A: Detection by immune electron microscopy of a viruslike antigen associated with acute illness, Science, 182, pp. 1026-1028, (1973)
[3]  
Health Topics in Hepatitis, (2002)
[4]  
Robert-Koch-Institut, Zur Situation der Hepatitis A in Deutschland, 2004, Epidemiologisches Bulletin, 14, pp. 119-126, (2005)
[5]  
Bell B.P., Kruszon-Moran D., Shapiro C.N., Et al., Hepatitis A virus infection in the United States: Serologic results from theThird National Health and Nutrition Examination Survey, Vaccine, 23, pp. 5798-5806, (2005)
[6]  
Robert-Koch-Institut, Empfehlungen der Ständigen Impfkommission (STIKO) am Robert Koch-Institut / Stand Juli 2006, Epidemiologisches Bulletin, 30, pp. 235-254, (2006)
[7]  
Tong M.J., el-Farra N.S., Grew M., Clinical manifestations of Hepatitis A: Recent experience in a community teaching hospital, J Infect Dis, 171, SUPPL. 1, pp. 515-518, (1995)
[8]  
Jacobson I.M., Nath B.J., Dienstag J.L., Relapsing viral hepatitis type A, J Med Virol, 16, pp. 163-169, (1985)
[9]  
Keeffe E.B., Is Hepatitis A more severe in patients with chronic Hepatitis B and other chronic liver diseases?, Am J Gastroenterol, 90, pp. 201-205, (1995)
[10]  
Reichen J., Grob P.J., Hepatitis B virus infection: Diagnosis, clinical sequelae, therapy and prevention], Schweiz Rundsch Med Prax, 91, pp. 307-319, (2002)