Evaluation of a Single Dose Intravenous Paracetamol for Pain Relief After Maxillofacial Surgery: A Randomized Clinical Trial Study

被引：1

作者：

Eftekharian H. ^{[1
,2
]}

Tabrizi R. ^{[1
,2
,3
]}

Kazemi H. ^{[1
,2
]}

Nili M. ^{[2
]}

机构：

[1] Department of Maxillofacial Surgery, Shiraz University of Medical Science, Shiraz

[2] Shiraz University of Medical Science, Shiraz

[3] Chamran Hospital, CMF Ward, Chamran Avenue, Shiraz, Fars

来源：

Journal of Maxillofacial and Oral Surgery | 2014年 / 13卷 / 4期

关键词：

Maxillofacial surgery; Pain; Paracetamol; VAS;

D O I：

10.1007/s12663-013-0557-9

中图分类号：

学科分类号：

摘要：

Objective: The aim of this study was to evaluate, using a single dose of intravenous paracetamol, pain relief after maxillofacial surgery. Materials and Methods: This is a controlled, randomized, uni- blind, clinical trial study to evaluate using a single dose of IV paracetamol for pain relief after maxillofacial surgery. The subjects were randomly divided into two groups with 40 subjects in each: group I received paracetamol (Apotel)* as a single dose and group II received placebo. Subjects were randomly allocated according to randomization lists. Paracetamol was used as a single dose (20 mg/kg in 100 cc of normal saline which was infused for 10 min after surgery in recovery room just before discharging). We used a visual analogue scale to investigate pain relief at various times. Results: Analysis of the data, did not show any significant difference for age, sex and weight between the treatment group and the control group. Pain decreased 6 h after paracetamol infusion; then it increased mildly. In the control group, pain severity increased after operation, then it decreased mildly. Results showed a correlation between duration of surgery and pain severity in both the groups. Conclusion: Paracetamol is effective on pain relief after maxillofacial surgeries. Operation time may be an important factor for induction of pain after the surgeries. © 2013, Association of Oral and Maxillofacial Surgeons of India.

引用

页码：478 / 482

页数：4

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