Current concepts in the evaluation and management of syncope

被引：3

作者：

Kuriachan V. ^{[1
]}

Sheldon R.S. ^{[1
]}

机构：

[1] Cardiovascular Research Group, University of Calgary, Calgary, AB T2N 4N1

来源：

Current Cardiology Reports | 2008年 / 10卷 / 5期

关键词：

Structural Heart Disease; Lower Body Negative Pressure; Midodrine; Tilt Testing; Vasovagal Syncope;

D O I：

10.1007/s11886-008-0061-x

中图分类号：

学科分类号：

摘要：

Syncope is a very common presentation with a wide differential diagnosis and equally wide prognostic implications. Recent work has highlighted the importance of an accurate history and physical examination as the basis of diagnosis, prognosis, and treatment. Several centers have evaluated the role of structured histories and comprehensive syncope evaluation guidelines and units in managing syncope. Although these do provide comprehensive care, whether they improve overall outcome and reduce costs is far from clear. This is partly because there are few effective treatments for the major cause of fainting, vasovagal syncope. Recent randomized trials have highlighted the roles of physical counterpressure maneuvers and midodrine and the limitations of treatment with β blockers and permanent cardiac pacing. © Current Medicine Group LLC 2008.

引用

页码：384 / 390

页数：6

共 42 条

[31]

Sheldon R., Connolly S., Rose S., Et al., Prevention of Syncope Trial (POST): A randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope, Circulation, 113, pp. 1164-1170, (2006)

[32]

Flevari P., Livanis E.G., Theodorakis G.N., Et al., Vasovagal syncope: A prospective, randomized, crossover evalaution of the effect of propranolol, nadolol and placebo on syncope recurrence and patients' well-being, J Am Coll Cardiol, 40, pp. 499-504, (2002)

[33]

Girolomo E., Iorio C., Sabatini P., Et al., Effects of paroxetine hydrochloride, a selective serotonin reuptake inhibitor, on refractory vasovagal syncope: A randomized, double-blind, placebo-controlled study, J Am Coll Cardiol, 33, pp. 1227-1230, (1999)

[34]

Theodorakis G.N., Leftheriotis D., Livanis E.G., Et al., Fluoxetine vs. propranolol in the treatment of vasovagal syncope: A prospective, randomized, placebo-controlled study, Europace, 8, pp. 193-198, (2006)

[35]

Takata T.S., Wasmund S.L., Smith M.L., Et al., Serotonin reuptake inhibitor (Paxil) does not prevent the vasovagal reaction associated with carotid sinus massage and/or lower body negative pressure in healthy volunteers, Circulation, 106, pp. 1500-1504, (2002)

[36]

Salim M.A., Di Sessa T.G., Effectiveness of fludrocortisone and salt in preventing syncope recurrence in children: A double-blind, placebo-controlled, randomized trial, J Am Coll Cardiol, 45, pp. 484-488, (2005)

[37]

Qingyou Z., Junbao D., Chaoshu T., The efficacy of midodrine hydrochloride in the treatment of children with vasovagal syncope, J Pediatr, 149, pp. 777-780, (2006)

[38]

Sud S., Massel D., Klein G.J., Et al., The expectation effect and cardiac pacing for refractory vasovagal syncope, Am J Med, 120, pp. 54-62, (2007)

[39]

Connolly S.J., Sheldon R., Thorpe K.E., Et al., The Second Vasovagal Pacemaker Study (VPSII): A double-blind randomized controlled trial of pacemaker therapy for the prevention of syncope in patients with recurrent severe vasovagal syncope, JAMA, 290, pp. 1579-1580, (2003)

[40]

Raviele A., Giada F., Menozzi C., Et al., A randomized, double-blind, placebo-controlled study of permanent cardiac pacing for the treatment of recurrent tilt-induced vasovagal syncope. The vasovagal syncope and pacing trial (SYNPACE), Eur Heart J, 25, pp. 1741-1748, (2004)

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