Gastric carcinoma: Review of the results of treatment in a community teaching hospital

被引:12
作者
Heemskerk V.H. [1 ,2 ]
Lentze F. [1 ,3 ]
Hulsewé K.W.E. [1 ]
Hoofwijk T.G.M. [1 ]
机构
[1] Maaslandziekenhuis, Department of Surgery, Sittard
[2] Academisch Ziekenhuis Maastricht, Department of Surgery, Maastricht
[3] Atrium Medisch Centrum, Department of Surgery, Heerlen
关键词
Gastric Cancer; Gastric Carcinoma; Curative Intent; Palliative Resection; Linitis Plastica;
D O I
10.1186/1477-7819-5-81
中图分类号
学科分类号
摘要
Background: The aim of this study is to provide data on long term results of gastric cancer surgery and in particular the D1 gastric resection. Methods: In the period 1992-2004, 235 male and female patients with a median age of 69 and 70 years respectively, were included with a stage I through IV gastric carcinoma, of which 37% was stage IV disease. Whenever possible a gastric resection was performed. In case of obstructive tumour growth palliation was provided by means of a gastro-enterostomy. Results: Gastrectomy with curative intent was achieved in 50%, palliative resection in 22%, palliative surgery (gastro-enterostomy) in 10% and in 18% irresectability led to surgical exploration only. Patients in the curative intent group demonstrated a 47% survival after 5 years and up to 34% after 10 years. However metastases where seen in 32% of the patients after gastrectomy with curative intent. After palliative resection one year survival was 57%, whereas 19% survived more than 3 years. Overall postoperative morbidity and mortality rates were 40% and 13% respectively. Conclusion: Long term survival after surgery for gastric cancer is poor and is improved by early detection and radical resection. However, palliative resection showed improved survival compared to gastro-enterostomy alone or no resection at all which may be an effect of adjuvant therapy. © 2007 Heemskerk et al; licensee BioMed Central Ltd.
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