Synthesis of N-methylcarbazoles from N-(2-iodoaryl)-N-methylanilines in the presence of potassium tert-butoxide and iron(II) bromide

被引：0
作者：
I. Melnika
K. Bringis
M. Katkevics
机构：
[1] Latvian Institute of Organic Synthesis,
来源：
Chemistry of Heterocyclic Compounds | 2013年 / 49卷
关键词：
carbazole; cyclization; intramolecular diaryl bond formation; iron(II) catalysis; radical homolytic aromatic substitution;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
An effective and accessible method was developed for the preparation of N-methylcarbazoles from N-(2-iodoaryl)-N-methylanilines. Cyclization occurred in the presence of potassium tert-butoxide and iron(II) bromide by a mechanism of radical homolytic substitution. Two regioisomers were formed in cases when the aryl groups had meta- substituents relative to the amino group.
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页码：529 / 539
页数：10
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