Estimation of transmembrane potential of thymic lymphocytes during dexamethasone-induced apoptosis

被引：0
作者：
A. S. Dukhanin
D. V. Patrashev
机构：
[1] Russian State Medical University,
来源：
Bulletin of Experimental Biology and Medicine | 1999年 / 127卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The use of potential-sensitive fluorescent probes allowed us to estimate transmembrane potentials of the plasma (Δφp) and mitochondrial (Δφm) membranes of rat thymocytes, which were −58±3 mV and −169±7 mV, respectively. Dexamethasone-induced apoptosis led to a significant decrease in Δφp (by 55%) and Δφm (by 17%). This effects of dexamethasone was dose- and time-dependent. Changes in Δφm were greater and preceded those in Δφp.
引用
收藏
页码：106 / 109
页数：3
相关论文
共 32 条
  • [1] Dobretsov G. E.(1986)undefined Biol. Membr. 3 266-274
  • [2] Kosnikov V. V.(1985)undefined Biofizika 30 833-836
  • [3] Morozova G. I.(1998)undefined Immunologiya 1 15-18
  • [4] Dobretsov G. E.(1983)undefined Biofizika 28 160-170
  • [5] Morozova G. I.(1990)undefined Arkh. Anat. 99 68-77
  • [6] Barenboim G. M.(1993)undefined J. Cell. Physiol 154 199-206
  • [7] Dukhanin A. S.(1995)undefined News Physiol. Sci. (NIPS) 10 18-21
  • [8] Patrashev D. V.(1993)undefined Am. J. Physiol. 265 C1191-C1200
  • [9] Putvinskii A. V.(1995)undefined Nippon Rinsho 53 3113-3121
  • [10] Petrov V. V.(1982)undefined Nature 295 68-71
1234