Enantioseperation of chiral phenothiazine derivatives in capillary electrophoresis using cyclodextrin type chiral selectors

被引:0
作者
B. Chankvetadze
I. Kartozia
N. Burjanadze
D. Bergenthal
H. Luftmann
G. Blaschke
机构
[1] University of Münster,Institute of Pharmaceutical Chemistry
[2] Tbilisi State University,Molecular Recognition and Separation Science laboratory, School of Chemistry
来源
Chromatographia | 2001年 / 53卷
关键词
Capillary electrophoresis; Enantioseparations; Cyclodextrins; NMR spectrometry; Binding Constants;
D O I
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中图分类号
学科分类号
摘要
The enantioseparation of chiral phenothiazine derivatives has been studied in capillary electrophoresis (CE) using various cyclodextrins (CD) such as native α, β, and γ-CD and some of their neutral and charged derivatives. Comparative binding studies were performed using nuclear magnetic resonance (NMR) spectrometry. The advantages and disadvantages of the binding parameters obtained in both techniques (NMR and CE) from the viewpoint of separation optimization are discussed.
引用
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页码:S290 / S295
相关论文
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