Zinc as an adjunct treatment for reducing case fatality due to clinical severe infection in young infants: study protocol for a randomized controlled trial

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作者
Nitya Wadhwa
Sudha Basnet
Uma Chandra Mouli Natchu
Laxman P. Shrestha
Shinjini Bhatnagar
Halvor Sommerfelt
Tor A. Strand
Siddarth Ramji
K. C. Aggarwal
Harish Chellani
Anuradha Govil
Mamta Jajoo
N. B. Mathur
Meenakshi Bhatt
Anup Mohta
Imran Ansari
Srijana Basnet
Ram H. Chapagain
Ganesh P. Shah
Binod M. Shrestha
机构
[1] Pediatric Biology Centre,Department of Child Health, Institute of Medicine
[2] Translational Health Science and Technology Institute,Department of Neonatology
[3] Tribhuvan University,Department of Pediatrics
[4] Maulana Azad Medical College and associated Lok Nayak Hospital,Department of Pediatrics
[5] Vardhman Mahavir Medical College & Safdarjung Hospital,Department of Pediatric Medicine
[6] Kasturba Hospital,Department of Pediatric Surgery
[7] Chacha Nehru Bal Chikitsalaya,Department of Pediatrics
[8] Chacha Nehru Bal Chikitsalaya,Medical Department
[9] Patan Academy of Health Sciences,Centre for Intervention Science in Maternal and Child Health, Centre for International Health
[10] Kanti Children’s Hospital,Department of Research
[11] University of Bergen,undefined
[12] Innlandet Hospital Trust,undefined
来源
BMC Pharmacology and Toxicology | / 18卷
关键词
Sepsis; Severe infection; Infants; Neonate; Zinc; India; Nepal;
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[1]  
Liu L(2016)Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the sustainable development goals Lancet 388 3027-3035
[2]  
Oza S(2012)Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000 Lancet 379 2151-2161
[3]  
Hogan D(2005)Cousens S, Zupan J, Lancet neonatal survival steering team. 4 million neonatal deaths: when? Where? Why? Lancet 365 891-900
[4]  
Chu Y(2008)Clinical signs that predict severe illness in children under age 2 months: a multicentre study Lancet 371 135-142
[5]  
Perin J(2012)Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, double-blind, placebo-controlled trial Lancet 379 2072-2078
[6]  
Zhu J(1998)Zinc and immune function: the biological basis of altered resistance to infection Am J Clin Nutr 68 447S-463S
[7]  
Liu L(1998)Zinc and immunity Mol Cell Biochem 188 63-69
[8]  
Johnson HL(1997)Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children Indian Pediatr 34 589-597
[9]  
Cousens S(1963)Biochemical studies on dwarfism, hypogonadism, and anemia Arch Intern Med 111 407-428
[10]  
Perin J(2004)Assessment of the risk of zinc deficiency in populations Food Nutr Bull 25 S130-S162