A polyoxometalate based electrochemical sensor for efficient detection of L-cysteine

被引:0
作者
Ming-Yue Chu
Jia Jiao
Wei Zhu
Xin Yang
Ting-Ting Yu
Gui-Xin Yang
Hui-Yuan Ma
机构
[1] Harbin University of Science and Technology,School of Material Science and Chemical Engineering
[2] Harbin Institute of Petroleum,College of Chemical Engineering
来源
Tungsten | 2022年 / 4卷
关键词
L-cysteine; Phosphomolybadate; Cobalt (II) tetrasulfonate phthalocyanine; Electrochemical sensor;
D O I
暂无
中图分类号
学科分类号
摘要
L-cysteine (L-cys), as an important sulfur-containing amino acid, plays an indispensable role in biological systems. Too low and excessively high ratio of L-cys will cause harm to the function of human organs. Therefore, it is very necessary to develop efficient methods to detect it in multifarious samples. This paper has built an electrochemical sensor by combining Keggin-type polyoxometalate (PMo9V3) and cobalt tetrasulfonate (II) phthalocyanine (CoTsPc) on indium tin oxide electrodes using the layer-level self-assembly technology for efficiently detection of L-cys. The assembly process and surface morphology of the modified electrode was characterized by ultraviolet–visible spectroscopy, X-ray photoelectron spectroscopy, scanning electron microscope, and atomic force microscopy. The conditions of electro-catalysed oxidation of L-cys were optimized by cyclic voltammetry, and the kinetic electrochemical parameters were also evaluated by electrochemical impedance spectra. Furthermore, the sensing performance of the modified electrode was explored using amperometry. The proposed electrochemical L-cys sensor was found to have superior sensing performance with a range of linear response of 2.5 × 10–7 to 1.7 × 10–4 mol·L−1 and 1.7 × 10−4 to 39.5 × 10−4 mol·L−1, the detection limit of 1.0 × 10–7 mol·L−1 (signal/noise = 3), and satisfactory anti-interference ability. Consequently, the fabricated sensor has the potential to be applied in laboratory practices for L-cys deterimination in commercial drinks.
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页码:138 / 148
页数:10
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