The optimal glycemic target in critically ill patients: an updated network meta-analysis

被引：1
作者：
Tanaka, Aiko [1 ,2 ]
Yatabe, Tomoaki [3 ]
Suhara, Tomohiro [4 ]
Egi, Moritoki [5 ]
机构：
[1] Univ Fukui Hosp, Dept Intens Care, 23-3 Matsuoka Shimoaizuki,Eiheiji Cho, Fukui 9101193, Japan
[2] Osaka Univ, Grad Sch Med, Dept Anesthesiol & Intens Care Med, 2-15 Yamadaoka, Suita, Osaka 5650871, Japan
[3] Nishichita Gen Hosp, Emergency Dept, 3-1-1 Nakanoike, Tokai, Aichi 4778522, Japan
[4] Keio Univ, Sch Med, Dept Anesthesiol, 35 Shinanomachi,Shinjuku Ku, Tokyo 1608582, Japan
[5] Kyoto Univ Hosp, Dept Anesthesia, 54 Shogoin Kawahara Cho,Sakyo Ku, Kyoto 6068507, Japan
来源：
JOURNAL OF INTENSIVE CARE | 2024年 / 12卷 / 01期
关键词：
Glycemic control; Blood glucose; Optimal target; Critical care; Network meta-analysis; INTENSIVE INSULIN THERAPY; GLUCOSE CONTROL;
D O I：
10.1186/s40560-024-00728-0
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Acute glycemic control significantly affects the clinical outcomes of critically ill patients. This updated network meta-analysis examines the benefits and harms of four target blood glucose levels (< 110, 110-144, 144-180, and > 180 mg/dL). Analyzing data of 27,541 patients from 37 trials, the surface under the cumulative ranking curve for mortality and hypoglycemia was highest at a target blood glucose level of 144-180 mg/dL, while for infection and acute kidney injury at 110-144 mg/dL. Further evidence is needed to determine whether 110-144 or 144-180 mg/dL is superior as an optimal glucose target, considering prioritized outcomes.
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页数：5
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