Hippocampal CA1 βCaMKII mediates neuroinflammatory responses via COX-2/PGE2 signaling pathways in depression

[1] Papakostas GI(2015)Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder Mol Psychiatry 20 1142-1150

[2] Ionescu DF(2009)Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression Biol Psychiatry 65 732-741

[3] Miller AH(2002)Decreased prefrontal CaMKII alpha mRNA in bipolar illness Neuroreport 13 501-505

[4] Maletic V(2004)Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus Int J Neuropsychopharmacol 7 299-309

[5] Raison CL(2006)Increased expression of calcium/calmodulin-dependent protein kinase IIbeta in frontal cortex in schizophrenia and depression Synapse 59 61-68

[6] Xing G(2004)Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders Int J Neuropsychopharmacol 7 243-248

[7] Russell S(2014)CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture J Neuroinflammation 11 90-98

[8] Hough C(2018)GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription Neuropharmacology 35 536-546

[9] O'Grady J(2013)βCaMKII in lateral habenula mediates core symptoms of depression Science 341 1016-1020

[10] Zhang L(2005)Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis Neuroscience 133 437-451

[1] Papakostas GI(2015)Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder Mol Psychiatry 20 1142-1150

[2] Ionescu DF(2009)Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression Biol Psychiatry 65 732-741

[3] Miller AH(2002)Decreased prefrontal CaMKII alpha mRNA in bipolar illness Neuroreport 13 501-505

[4] Maletic V(2004)Influence of immobilization stress on the levels of CaMKII and phospho-CaMKII in the rat hippocampus Int J Neuropsychopharmacol 7 299-309

[5] Raison CL(2006)Increased expression of calcium/calmodulin-dependent protein kinase IIbeta in frontal cortex in schizophrenia and depression Synapse 59 61-68

[6] Xing G(2004)Focus on CaMKII: a molecular switch in the pathophysiology and treatment of mood and anxiety disorders Int J Neuropsychopharmacol 7 243-248

[7] Russell S(2014)CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture J Neuroinflammation 11 90-98

[8] Hough C(2018)GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription Neuropharmacology 35 536-546

[9] O'Grady J(2013)βCaMKII in lateral habenula mediates core symptoms of depression Science 341 1016-1020

[10] Zhang L(2005)Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis Neuroscience 133 437-451