The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells

被引:0
|
作者
Katja Linher-Melville
Gurmit Singh
机构
[1] McMaster University,Department of Pathology and Molecular Medicine
来源
BMC Cancer | / 14卷
关键词
Breast cancer; STAT3; STAT5; LKB1; Prolactin; Interleukin 6; Promoter; Transcriptional regulation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells
    Nair, Varun Sasidharan
    Toor, Salman M.
    Ali, Bassam R.
    Elkord, Eyad
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2018, 22 (06) : 547 - 557
  • [22] Cucurbitacin D exhibits its anti-cancer effect in human breast cancer cells by inhibiting Stat3 and Akt signaling
    Ku, Jin Mo
    Hong, Se Hyang
    Kim, Hyo In
    Lim, Ye Seul
    Lee, Sol Ji
    Kim, Mia
    Seo, Hye Sook
    Shin, Yong Cheol
    Ko, Seong-Gyu
    EUROPEAN JOURNAL OF INFLAMMATION, 2018, 16 : 1 - 9
  • [23] Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
    Y Huang
    X Li
    J Jiang
    S J Frank
    Oncogene, 2006, 25 : 7565 - 7576
  • [24] Discovery of imidazopyridine-pyrazoline-hybrid structure as SHP-1 agonist that suppresses phospho-STAT3 signaling in human breast cancer cells
    Yang, Min Hee
    Sethi, Gautam
    Ravish, Akshay
    Mohan, Arun Kumar
    Pandey, Vijay
    Lobie, Peter E.
    Basappa, Shreeja
    Basappa, Basappa
    Ahn, Kwang Seok
    CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 386
  • [25] Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells
    Huang, Y.
    Li, X.
    Jiang, J.
    Frank, S. J.
    ONCOGENE, 2006, 25 (58) : 7565 - 7576
  • [26] Integrin β 1,-mediated invasion of human breast cancer cells: An ex vivo assay for invasiveness
    Berry M.G.
    Goode A.W.
    Puddefoot J.R.
    Vinson G.P.
    Carpenter R.
    Breast Cancer, 2003, 10 (3) : 214 - 219
  • [27] SNAI1-mediated transcriptional regulation of epithelial-to-mesenchymal transition genes in breast cancer stem cells
    Singh, Digvijay
    Deshmukh, Rohit K.
    Das, Amitava
    CELLULAR SIGNALLING, 2021, 87
  • [28] Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells
    Kim, Na Hui
    Sung, Nam Ji
    Youn, Hyung-Sun
    Park, Sin-Aye
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 533 (04) : 1378 - 1384
  • [29] Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway
    Sung, Nam Ji
    Kim, Na Hui
    Surh, Young-Joon
    Park, Sin-Aye
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (23) : 1 - 15
  • [30] A Rac–Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells
    L E Arias-Romero
    O Villamar-Cruz
    A Pacheco
    R Kosoff
    M Huang
    S K Muthuswamy
    J Chernoff
    Oncogene, 2010, 29 : 5839 - 5849