Efficacy and Safety of 24 Weeks of Therapy with Bendroflumethiazide 1.25 mg/day or 2.5 mg/day and Potassium Chloride Compared with Enalapril 10 mg/day and Amlodipine 5 mg/day in Patients with Mild to Moderate Primary HypertensionA Multicentre, Randomised, Open Study

被引:0
作者
S. Rasmussen
N. Borrild
J. Vang Andersen
机构
[1] Hilleroed Hospital,Medical Department B
来源
Clinical Drug Investigation | 2006年 / 26卷
关键词
Diastolic Blood Pressure; Enalapril; Amlodipine; Potassium Chloride; Thiazide Diuretic;
D O I
暂无
中图分类号
学科分类号
摘要
Background: The efficacy and safety of therapy with low-dose bendroflumethiazide 1.25 mg/day or 2.5 mg/day and potassium chloride was compared with that of enalapril 10 mg/day and amlodipine 5 mg/day in patients with mild to moderate primary hypertension.
引用
收藏
页码:91 / 101
页数:10
相关论文
共 36 条
[1]  
Chobanian A.V.(2003)The seventh report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure JAMA 289 2560-72
[2]  
Bakris G.L.(1999)Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity: the Swedish trial in Old Patients with Hypertension-2 study Lancet 354 1751-6
[3]  
Black H.R.(1999)Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) Lancet 353 611-6
[4]  
Hansson L.(2000)Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifidipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT) Lancet 356 366-72
[5]  
Lindholm L.H.(2000)Randomised trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) Study Lancet 356 359-65
[6]  
Ekbom T.(2003)A comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretics for hypertension in the elderly N Engl J Med 348 583-92
[7]  
Hansson L.(2002)Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic. The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT) JAMA 288 2981-97
[8]  
Lindholm L.H.(2002)The verdict from ALLHAT: thiazide diuretics are the preferred initial therapy for hypertension JAMA 288 3039-42
[9]  
Niskanen L.(1990)Relation between dose of bendrofluazide, antihypertensive effect, and adverse biochemical effects BMJ 300 975-8
[10]  
Brown M.J.(1993)Double blind, parallel, comparative study on quality of life during treatment with amlodipine or enalapril in mild or moderate hypertensive patients: a multicentre study J Hypertens 11 103-13