Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington’s disease peripheral blood samples

被引：0

作者：

Anastasios Mastrokolias

Rene Pool

Eleni Mina

Kristina M. Hettne

Erik van Duijn

Roos C. van der Mast

GertJan van Ommen

Peter A. C. ‘t Hoen

Cornelia Prehn

Jerzy Adamski

Willeke van Roon-Mom

机构：

[1] Leiden University Medical Center,Department of Human Genetics

[2] VU University Amsterdam,Department of Biological Psychology, Faculty of Psychology and Education

[3] VU University Medical Center,The EMGO + Institute for Health and Care Research

[4] Leiden University Medical Center,Department of Psychiatry

[5] Center for Mental Health Care Delfland,Helmholtz Zentrum, München, German Research Center for Environmental Health, Institute of Experimental Genetics

[6] Genome Analysis Center,Lehrstuhl für Experimentelle Genetik

[7] German Center for Diabetes Research,undefined

[8] Technische Universität München,undefined

来源：

Metabolomics | 2016年 / 12卷

关键词：

Metabolomics; Gene expression; Biomarkers; Disease progression; Neurodegenerative; Integrated analysis;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 7 条

[1] Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples
Mastrokolias, Anastasios
Pool, Rene
Mina, Eleni
Hettne, Kristina M.
van Duijn, Erik
van der Mast, Roos C.
van Ommen, GertJan
't Hoen, Peter A. C.
Prehn, Cornelia
Adamski, Jerzy
van Roon-Mom, Willeke
METABOLOMICS, 2016, 12 (08)
[2] Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington's disease monkeys
Kocerha, Jannet
Liu, Yuhong
Willoughby, David
Chidamparam, Kumaravel
Benito, Joseph
Nelson, Kate
Xu, Yan
Chi, Tim
Engelhardt, Heidi
Moran, Sean
Yang, Shang-Hsun
Li, Shi-Hua
Li, Xiao-Jiang
Larkin, Katherine
Neumann, Adam
Banta, Heather
Yang, Jin Jing
Chan, Anthony W. S.
BMC NEUROSCIENCE, 2013, 14
[3] Comprehensive blood metabolomics profiling of Parkinson's disease reveals coordinated alterations in xanthine metabolism
de Lope, Elisa Gomez
Loo, Rebecca Ting Jiin
Rauschenberger, Armin
Ali, Muhammad
Pavelka, Lukas
Marques, Taina M.
Gomes, Clarissa P. C.
Kruger, Rejko
Glaab, Enrico
NPJ PARKINSONS DISEASE, 2024, 10 (01)
[4] RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease
Andrade-Navarro, Miguel A.
Muhlenberg, Katja
Spruth, Eike J.
Mah, Nancy
Gonzalez-Lopez, Adrian
Andreani, Tommaso
Russ, Jenny
Huska, Matthew R.
Muro, Enrique M.
Fontaine, Jean-Fred
Amstislavskiy, Vyacheslav
Soldatov, Alexei
Nietfeld, Wilfried
Wanker, Erich E.
Priller, Josef
FRONTIERS IN NEUROLOGY, 2020, 11
[5] Metabolomics profiling reveals altered lipid metabolism and identifies a panel of lipid metabolites as biomarkers for Parkinson's disease related anxiety disorder
Dong, Mei-Xue
Hu, Ling
Wei, You-Dong
Chen, Guang-Hui
NEUROSCIENCE LETTERS, 2021, 745
[6] Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients
Askeland, Georgina
Dosoudilova, Zaneta
Rodinova, Marie
Klempir, Jiri
Liskova, Irena
Kusnierczyk, Anna
Bjoras, Magnar
Nesse, Gaute
Klungland, Arne
Hansikova, Hana
Eide, Lars
SCIENTIFIC REPORTS, 2018, 8
[7] Baseline Peripheral Blood Mononuclear Cell Transcriptomics Before Ustekinumab Treatment Is Linked With Crohn's Disease Clinical Response at 1 Year
Granot, Maya
Braun, Tzipi
Efroni, Gilat
Picard, Orit
Fudim, Ella
Yavzori, Miri
Haj, Ola
Weiss, Batia
Ben-Horin, Shomron
Kopylov, Uri
Haberman, Yael
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 2023, 14 (12) : e00635

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