Molecular analysis of trkC in the cat visual cortex

被引:0
作者
Farzin Forooghian
Ljubomir Kojic
Qiang Gu
Christian A. Wong
Shiv S. Prasad
机构
[1] University of British Columbia,Department of Ophthalmology
[2] University of British Columbia,Department of Anatomy
[3] University of British Columbia,Brain Research Center
来源
Journal of Molecular Neuroscience | 2000年 / 14卷
关键词
Cat; DNA sequence analysis; RT-PCR; visual cortex; neurotrophins; C;
D O I
暂无
中图分类号
学科分类号
摘要
trkC belongs to the trk family of neurotrophin receptors. Several isoforms of trkC have been cloned to date; a full-length catalytic form containing a tyrosine kinase (TK) domain, three full-length isoforms with amino-acid insertions (14, 25, and 39 amino acids) in the TK domain, and five noncatalytic truncated forms that completely lack the TK domain. These isoforms have been studied in several mammalian species, including the pig, rat, mouse, monkey, and human.
引用
收藏
页码:39 / 51
页数:12
相关论文
共 158 条
[31]  
Ghosh A.(1998) proto-oncogene J. Comp. Neurol. 401 47-64
[32]  
Gorba T.(1992)Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth Neuroscience 3 513-532
[33]  
Wahle P.(1991)Neurotrophins and synaptic plasticity Mol. Cell. Biol. 11 143-153
[34]  
Gu Q.(1999)Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant J. Comp. Neurol. 408 378-398
[35]  
Gu Q.(2000)The nerve growth factor family of receptors Curr. Opin. Neurol. 9 122-125
[36]  
Liu Y.(1977)Differential expression of TrkC catalytic and noncatalytic isoforms suggest that they act independently or in association Proc. Natl. Acad. Sci. USA 74 5463-5467
[37]  
Cynader M.(1991)Molecular cloning of rat Oncogene 6 1807-1811
[38]  
Hanks S. K.(1995)C and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nerbous system J. Neurosci. 15 477-491
[39]  
Quinn A. M.(1997)Trk B, a neural receptor-protein kinase: evidence for a full-length and two truncated receptors Curr. Biol. 7 627-630
[40]  
Hunter T.(1995)Quantitative evaluation of neurotrophin and Science 270 593-598