Autophagy mediates degradation of nuclear lamina

被引：0

作者：

Zhixun Dou

Caiyue Xu

Greg Donahue

Takeshi Shimi

Ji-An Pan

Jiajun Zhu

Andrejs Ivanov

Brian C. Capell

Adam M. Drake

Parisha P. Shah

Joseph M. Catanzaro

M. Daniel Ricketts

Trond Lamark

Stephen A. Adam

Ronen Marmorstein

Wei-Xing Zong

Terje Johansen

Robert D. Goldman

Peter D. Adams

Shelley L. Berger

机构：

[1] Epigenetics Program,Department of Cell and Developmental Biology

[2] Perelman School of Medicine,Department of Cell and Molecular Biology

[3] University of Pennsylvania,Department of Molecular Genetics and Microbiology

[4] Feinberg School of Medicine,Department of Biochemistry & Biophysics

[5] Northwestern University,Department of Chemistry

[6] Stony Brook University,undefined

[7] Institute of Cancer Sciences,undefined

[8] University of Glasgow and Beatson Institute for Cancer Research,undefined

[9] University of Pennsylvania,undefined

[10] Molecular Cancer Research Group,undefined

[11] Institute of Medical Biology,undefined

[12] University of Tromsø – The Arctic University of Norway,undefined

[13] University of Pennsylvania,undefined

[14] Abramson Family Cancer Research Institute,undefined

[15] University of Pennsylvania,undefined

[16] † Present address: Centre for Haemato-Oncology,undefined

[17] Barts Cancer Institute,undefined

[18] Queen Mary University of London,undefined

[19] Charterhouse Square,undefined

[20] London EC1M 6BQ,undefined

[21] UK.,undefined

来源：

Nature | 2015年 / 527卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

In response to cancer-associated stress, autophagy machinery mediates degradation of nuclear lamina components in mammals, suggesting that cells might degrade nuclear components to prevent tumorigenesis.

引用

页码：105 / 109

页数：4

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