Viral suppression of RNA silencing

被引：0
作者：
Lin Jiang
ChunHong Wei
Yi Li
机构：
[1] Peking University,State Key Laboratory of Protein and Plant Gene Research, College of Life Sciences
来源：
Science China Life Sciences | 2012年 / 55卷
关键词：
RNA silencing; viral suppressor of RNA silencing; mechanisms;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Gene silencing (RNA silencing) plays a fundamental role in antiviral defense in plants, fungi and invertebrates. Viruses encode proteins that suppress gene silencing to counter host defense. Viral suppressors of RNA silencing (VSRs) have been identified from almost all plant virus genera and some viruses of insects and mammals. Recent studies have revealed that VSRs counter host defense and interfere with host gene regulation by interacting with RNA or important components of the RNA silencing pathway. Here, we review the current understanding of the complex mechanisms of VSRs that have been revealed by recent studies.
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页码：109 / 118
页数：9
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