A case of severe ovarian hyperstimulation syndrome

被引:2
作者
Lodh M. [1 ]
Mukhopadhyay J. [2 ]
Sharma V. [3 ]
机构
[1] Department of Biochemistry, Mission Hospital, Bidhannagar, Durgapur 713212, West Bengal, Imon Kalyan Sarani
[2] Department of Obstetrics and Gynaecology, Mission Hospital, Durgapur, West Bengal
[3] Department of Radiology, Mission Hospital, Durgapur, West Bengal
关键词
Anti cardiolipin antibodies; Assisted reproduction; Gonadotropin; Ovarian hyperstimulation syndrome; Ovarian stimulation; Ovulation induction;
D O I
10.1007/s12291-013-0390-4
中图分类号
学科分类号
摘要
Ovulation induction has been an important mode of treatment of infertility. Ovarian stimulation may result in a supraphysiologic response leading to an iatrogenic complication known as the ovarian hyperstimulation syndrome (OHSS). This syndrome is potentially a lethal condition, the pathophysiologic hallmark of which is the accumulation of massive extravascular exudate combined with profound intravascular volume depletion and hemoconcentration. We report a case of severe OHSS with very large ovaries in a 35 year old case of embryo transfer. The patient presented to the emergency department with abdominal pain, massive ascites, respiratory distress and amenorrhea. The patient was managed symptomatically with no complications. Although ovarian hyperstimulation is a rare entity, it is important that the physician recognizes this condition. Prompt diagnosis and successful management is likely to avoid serious and rapid development of complications. © 2013 Association of Clinical Biochemists of India.
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页码:386 / 389
页数:3
相关论文
共 11 条
[1]  
Alper M.M., Smith L.P., Sills E.S., Ovarian hyperstimulation syndrome: Current views on pathophysiology, risk factors, prevention, and management, J Exp Clin Assist Reprod, 6, (2009)
[2]  
Nastri C.O., Ferriani R.A., Rocha I.A., Martins W.P., Ovarian hyperstimulation syndrome: Pathophysiology and prevention, J Assist Reprod Genet, 27, pp. 121-128, (2010)
[3]  
Fiedler K., Ezcurra D., Predicting and preventing ovarian hyperstimulation syndrome (OHSS): The need for individualized not standardized treatment, Reprod Biol Endocrinol, 10, (2012)
[4]  
D'Angelo A., Davies R., Salah E., Nix B.A., Amso N.N., Value of the serum estradiol level for preventing ovarian hyperstimulation syndrome: A retrospective case control study, Fertility and Sterility, 81, 2, pp. 332-336, (2004)
[5]  
Grossman L.C., Michalakis K.G., Browne H., Payson M.D., Segars J.H., The pathophysiology of ovarian hyperstimulation syndrome: An unrecognized compartment syndrome, Fertil Steril, 94, 4, pp. 1392-1398, (2010)
[6]  
Gysler M., Hemmings R., Cheung A.P., Goodrow G.J., Hughes E.G., Min J.K., Et al., The diagnosis and management of ovarian hyperstimulation syndrome, J Obstet Gynaecol Can, 33, 11, pp. 1156-1162, (2011)
[7]  
Elchalal U., Schenker J.G., The pathophysiology of ovarian hyperstimulation syndrome - Views and ideas, Human Reproduction, 12, 6, pp. 1129-1137, (1997)
[8]  
Nabriski D., Ellis M., Ness-Abramof R., Shapiro M., Shenkman L., Autoimmune thyroid disease and antiphospholipid antibodies, American Journal of Hematology, 64, 1, pp. 73-75, (2000)
[9]  
Papanikolaou E.G., Humaidan P., Polyzos N., Kalantaridou S., Kol S., Benadiva C., Et al., New algorithm for OHSS prevention, Reprod Biol Endocrinol, 9, (2011)
[10]  
Choi M.H., Lee S.H., Kim H.O., Cha S.H., Kim J.Y., Yang K.M., Et al., Comparison of assisted reproductive technology outcomes in infertile women with polycystic ovary syndrome: In vitro maturation, GnRH agonist, and GnRH antagonist cycles, Clin Exp Reprod Med, 39, 4, pp. 166-171, (2012)