A case of rhinolaryngoscleroma in a patient with neurofibromatosis type 1

被引：1

作者：

Effat K.G. ^{[1
]}

机构：

[1] Department of Otolaryngology, El-Sahel Teaching Hospital, Cairo

来源：

The Egyptian Journal of Otolaryngology | 2013年 / 29卷 / 1期

关键词：

genetic disease; granuloma; immunity; neurofibromatosis; scleroma;

D O I：

10.7123/01.EJO.0000423982.18447.fc

中图分类号：

学科分类号：

摘要：

Abstract Introduction: Scleroma is a chronic-specific granuloma of the nose and it may involve other parts of the respiratory tract. The condition is endemic in Egypt. Neurofibromatosis type 1 (NF-1) is one of the most common genetic conditions of the nervous system. Before this report, no case had been published documenting scleroma in a patient with NF-1. Aim: To describe a case of rhinolaryngoscleroma in a patient with NF-1. Methods: Case report and literature review. Results: Presentation of clinical, imaging and pathological findings, as well as management considerations. Conclusion: This is the first case to be reported in the literature documenting the coexistence of rhinolaryngoscleroma and NF-1. The biological events in the immune system await further studies. © 2013, The Egyptian Oto - Rhino - Laryngological Society.

引用

页码：46 / 48

页数：2

共 20 条

[1]

Gaafar H.A., Gaafar A.H., Nour Y.A., Rhinoscleroma: an updated experience through the last 10 years, Acta Otolaryngol., 131, pp. 440-446, (2011)

[2]

Fawaz S., Tiba M., Salman M., Othman H., Clinical radiological and pathological study of 88 cases of typical and complicated scleroma, Clin Respir J., 5, pp. 112-121, (2011)

[3]

Duong T.A., Bastuji-Garin S., Valeyrie-Allanore L., Sbidian E., Ferkal S., Wolkenstein P., Evolving pattern with age of cutaneous signs in neurofibromatosis type 1: a cross-sectional study of 728 patients, Dermatology, 222, pp. 269-273, (2011)

[4]

Blessmann M., Grobe A., Quaas A., Kaifi J.T., Mistakidis G., Bernreuther C., Et al., Adhesion molecule L1 is down-regulated in malignant peripheral nerve sheath tumors versus benign neurofibromatosis type 1-associated tumors, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 113, pp. 239-244, (2012)

[5]

Petramala L., Giustini S., Zinnamosca L., Marinelli C., Colangelo L., Cilenti G., Et al., Bone mineral metabolism in patients with neurofibromatosis type 1 (von Recklinghausen disease), Arch Dermatol Res, 304, pp. 325-331, (2012)

[6]

Kehrer-Sawatzki H., Vogt J., Mubetaotter T., Kluwe L., Cooper D.N., Mautner V.-F., Dissecting the clinical phenotype associated with mosaic type-2 NF1 microdeletions, Neurogenetics, (2012)

[7]

Lee J.-H., Bae J.H., Kim K.-S., A case of solitary neurofibroma of the nasal dorsum: resection using an external rhinoplasty approach, Eur Arch Otorhinolaryngol., 262, pp. 813-815, (2005)

[8]

Amoils C.P., Shindo M.L., Laryngotracheal manifestations of rhinoscleroma, Ann Otol Rhinol Laryngol., 105, pp. 336-340, (1996)

[9]

Rifai M., Laryngotracheal resection for post scleromatous laryngeal stenosis, J Laryngol Otol., 103, pp. 935-938, (1989)

[10]

Friedrich R.E., Holstein A.-F., Middendorff R., Davidoff M.S., Vascular wall cells contribute to tumourigenesis in cutaneous neurofibromas of patients with neurofibromatosis type 1. A comparative histological, ultrastructural and immunohistochemical study, Anticancer Res., 32, pp. 2139-2158, (2012)

← 1 2 →