Aspirin resistance – does it clinically matter?

被引:0
作者
Karsten Schrör
T. Hohlfeld
A.-A. Weber
机构
[1] Universitätsklinikum Düsseldorf,Institut für Pharmakologie und Klinische Pharmakologie
[2] Heinrich-Heine-Universität,undefined
来源
Clinical Research in Cardiology | 2006年 / 95卷
关键词
“Aspirin resistance”; platelet function; thromboxane; coronary prevention;
D O I
暂无
中图分类号
学科分类号
摘要
A variable responsivenessto acetylsalicylic acid(ASA) is a clinical reality that doesnot principally differ from variableresponses to other kinds of drugtreatment in other therapeuticfields. Two questions arise: (i) isany resulting “treatment failure”due to a pharmacological failure ofthe drug to act and (ii) is any reducedantiplatelet activity to ASArelated to the clinical outcome ofthe patient?
引用
收藏
页码:505 / 510
页数:5
相关论文
共 50 条
  • [41] The antithrombotic profile of aspirin. Aspirin resistance, or simply failure?
    Altman R.
    Luciardi H.L.
    Muntaner J.
    Herrera R.N.
    Thrombosis Journal, 2 (1)
  • [42] Multiple Electrode Aggregometry is an adequate method for aspirin response testing in myeloproliferative neoplasms and differentiates the mechanisms of aspirin resistance
    Gillet, Benjamin
    Ianotto, Jean-Christophe
    Mingant, Fanny
    Didier, Romain
    Gilard, Martine
    Ugo, Valerie
    Lippert, Eric
    Galinat, Hubert
    THROMBOSIS RESEARCH, 2016, 142 : 26 - 32
  • [43] The impact of intravenous aspirin administration on platelet aspirin resistance after on-pump coronary artery bypass surgery
    Bach, Juergen
    Kammerer, Inna
    Isgro, Frank
    Haubelt, Hannelore
    Vogt, Anette
    Saggau, Werner
    Hellstern, Peter
    PLATELETS, 2009, 20 (03) : 150 - 157
  • [44] FREQUENCY OF ASPIRIN RESISTANCE IN PATIENTS WITH CORONORY ARTERY DISEASE IN PAKISTAN
    Akhtar, Naveed
    Junaid, Ayesha
    Khalid, Ayesha
    Ahmed, Waqas
    Shah, Mumtaz Ali
    Rahman, Habib Ur
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 22 (02) : 230 - 233
  • [45] Simvastatin administration reduces thromboxane production in subjects taking aspirin: Links between aspirin resistance and thrombin generation
    Undas, Anetta
    Siudak, Zbigniew
    Topor-Madry, Roman
    Lesniak, Marta
    Tracz, Wieslawa
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2012, 154 (01) : 59 - 64
  • [46] New direct and indirect methods for the detection of cyclooxygenase 1 acetylation by aspirin; the lack of aspirin resistance among healthy individuals
    Kovacs, Emese G.
    Katona, Eva
    Bereczky, Zsuzsanna
    Homorodi, Nora
    Balogh, Laszlo
    Toth, Eszter
    Peterfy, Hajna
    Kiss, Robert G.
    Edes, Istvan
    Muszbek, Laszlo
    THROMBOSIS RESEARCH, 2013, 131 (04) : 320 - 324
  • [47] Aspirin resistance in the era of personalized medicine: Should we not take it personally?
    Naimo, Phillip S.
    McGiffin, David
    Konstantinov, Igor E.
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2015, 150 (06) : E99 - E100
  • [48] Clinical importance of aspirin and clopidogrel resistance
    Feher, Gergely
    Feher, Andrea
    Pusch, Gabriella
    Koltai, Katalin
    Tibold, Antal
    Gasztonyi, Beata
    Papp, Elod
    Szapary, Laszlo
    Kesmarky, Gabor
    Toth, Kalman
    WORLD JOURNAL OF CARDIOLOGY, 2010, 2 (07): : 171 - 186
  • [49] The effectiveness of antioxidant therapy in aspirin resistance, diabetes population for prevention of thrombosis
    Aboonabi, Anahita
    Singh, Indu
    BIOMEDICINE & PHARMACOTHERAPY, 2016, 83 : 277 - 282
  • [50] Aspirin resistance in Indian patients with coronary artery disease and cardiovascular events
    Thomson, V. S.
    John, B.
    George, P.
    Joseph, G.
    Jose, J.
    JOURNAL OF POSTGRADUATE MEDICINE, 2009, 55 (04) : 252 - 256