Effect of Glyprolines PGP, GP, and PG on Homeostasis of Gastric Mucosa in Rats with Experimental Ethanol-Induced Gastric Ulcers

被引：0
作者：
T. M. Falalyeyeva
G. E. Samonina
T. V. Beregovaya
L. A. Andreeva
E. A. Dvorshchenko
机构：
[1] Biological Faculty of M. V. Lomonosov Moscow State University,Department of Human and Animal Physiology
[2] Biological Faculty of T. G. Shevchenko Kiev State University,Department of Pharmacology and Physiology
[3] Institute of Molecular Genetics,undefined
[4] Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2010年 / 149卷
关键词：
glyprolines; ethanol; gastric mucosa; lipid peroxidation; antioxidant enzymes;
D O I：
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学科分类号：
摘要：
The decrease in the severity of erosions and ulcer lesions after preventive treatment with PGP or PG correlated with a decrease in the content of lipid peroxidation products to a control level. Activities of SOD and catalase also returned to control values. GP produced the weakest effect on pro- and antioxidant state of the gastric mucosa. We concluded that the pronounced preventive effect of PGP and PG on the development of ethanol-induced erosions and ulcer lesions is largely determined by their antioxidant properties. Glyprolines can be considered as a promising means for prevention and treatment of stomach and duodenal ulcers.
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页码：699 / 701
页数：2
相关论文
共 19 条
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Ashmarin IP(2007)undefined Neirokhimiya 24 5-7
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[9]  
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[10]  
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