Synthesis of new indazole derivatives as potential antioxidant agents

被引：0
作者：
Majal Sapnakumari
Badiadka Narayana
Balladka Kunhanna Sarojini
Leelavathi Narayana Madhu
机构：
[1] Mangalore University,Department of Studies in Chemistry
[2] P.A. College of Engineering,Research Department of Chemistry
[3] St. Aloysius College,Post Graduation Department of Biochemistry
来源：
Medicinal Chemistry Research | 2014年 / 23卷
关键词：
Chalcone; Cyclohexenone; Indazole; Antioxidant activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New indazole derivatives were synthesized by reacting hydrazine hydrate and its derivatives with cyclohexenone derivatives, which in turn prepared from respective chalcones. The chemical structure of newly synthesized compounds was well characterized by using 1H NMR, 13C NMR, IR and mass spectral data. All the synthesized products were screened for their antioxidant properties. All indazole derivatives exhibited noticeable DPPH radical scavenging activity, reducing power capacity and total antioxidant capacity in comparison with the respective standards.
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页码：2368 / 2376
页数：8
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