Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation

被引:0
|
作者
Lilian Kabeche
Duane A. Compton
机构
[1] Geisel School of Medicine at Dartmouth,Department of Biochemistry
[2] Norris Cotton Cancer Center,undefined
来源
Nature | 2013年 / 502卷
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摘要
Cyclin A is shown to maintain unstable kinetochore–microtubule (k–MT) attachments in prometaphase in order to allow for error correction; at the prometaphase–metaphase switch, k-MT attachments are stabilized when cyclin A drops below threshold levels.
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页码:110 / 113
页数:3
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