Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation

被引:0
作者
Dan Li
Jiefei Zhou
Lingyu Wang
Zizhen Gong
Huijuan Le
Ye Huang
Congfeng Xu
Chunyan Tian
Wei Cai
Jin Wu
机构
[1] Xinhua Hospital,Department of Pediatric Surgery
[2] School of Medicine,Department of Cardiology
[3] Shanghai Jiaotong University,State Key Laboratory of Proteomics
[4] Shanghai Institute for Pediatric Research,Research Unit of Proteomics
[5] School of Medicine,Driven Cancer Precision Medicine
[6] Shanghai Jiaotong University,undefined
[7] Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition,undefined
[8] Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,undefined
[9] Beijing Proteome Research Center,undefined
[10] National Center for Protein Sciences (Beijing),undefined
[11] Beijing Institute of Lifeomics,undefined
[12] Chinese Academy of Medical Sciences,undefined
来源
Cell & Bioscience | / 13卷
关键词
Colonic inflammation; High fat diet; Bile acid; Th17 differentiation;
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