Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta

Maynard S(2003)Excess placental soluble fms-like tyrosine kinase 1 (sFlt-1) may contribute to endothelial dysfunction, hypertension, and proteinuria in pre-eclampsia J Clin Invest 111 649-658

Min JY(2006)Soluble endoglin contributes to the pathogenesis of preeclampsia Nat Med 12 642-649

Merchan J(2005)Latest advances in understanding preeclampsia Science 308 1592-1594

Lim KH(2005)Pre-eclampsia Lancet 365 785-799

Li J(2011)Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease Circulation 123 2856-2869

Mondal S(2010)Pathogenesis of preeclampsia Annu Rev Pathol 5 173-192

Libermann TA(2014)Pre-eclampsia part 1: current understanding of its pathophysiology Nat Rev Nephrol 10 466-480

Morgan JP(2014)Pre-eclampsia part 2: prediction, prevention and management Nat Rev Nephrol 10 531-540

Sellke FW(2007)Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1 Circulation 115 1789-1797

Stillman IE(2010)Using pravastatin to improve the vascular reactivity in a mouse model of soluble fms-like tyrosine kinase-1-induced preeclampsia Obstet Gynecol 116 114-120

Maynard S(2003)Excess placental soluble fms-like tyrosine kinase 1 (sFlt-1) may contribute to endothelial dysfunction, hypertension, and proteinuria in pre-eclampsia J Clin Invest 111 649-658

Min JY(2006)Soluble endoglin contributes to the pathogenesis of preeclampsia Nat Med 12 642-649

Merchan J(2005)Latest advances in understanding preeclampsia Science 308 1592-1594

Lim KH(2005)Pre-eclampsia Lancet 365 785-799

Li J(2011)Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease Circulation 123 2856-2869

Mondal S(2010)Pathogenesis of preeclampsia Annu Rev Pathol 5 173-192

Libermann TA(2014)Pre-eclampsia part 1: current understanding of its pathophysiology Nat Rev Nephrol 10 466-480

Morgan JP(2014)Pre-eclampsia part 2: prediction, prevention and management Nat Rev Nephrol 10 531-540

Sellke FW(2007)Negative regulation of soluble Flt-1 and soluble endoglin release by heme oxygenase-1 Circulation 115 1789-1797

Stillman IE(2010)Using pravastatin to improve the vascular reactivity in a mouse model of soluble fms-like tyrosine kinase-1-induced preeclampsia Obstet Gynecol 116 114-120