Laser Thermo-Photobiomodulation of Bone Marrow Mesenchymal Stem Cells

被引：0
作者：
R. K. Chailakhyan
A. G. Grosheva
N. N. Vorob’eva
A. P. Sviridov
V. I. Yusupov
机构：
[1] Ministry of Health of the Russian Federation,N. F. Gamaleya National Research Center of Epidemiology and Microbiology
[2] Institute of Photonic Technologies,Federal Research Center of Crystallography and Photonics, Russian Academy of Sciences
[3] Russian Academy of Sciences,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2023年 / 174卷
关键词：
mesenchymal stem cells; bone marrow; laser radiation; MSC colony formation; photobiomodulation;
D O I：
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中图分类号：
学科分类号：
摘要：
We studied the effect of laser radiation of moderate intensity with a wavelength of 970 nm on the efficiency of colony formation of rat bone marrow mesenchymal stem cells (MSC) in vitro. In this case, photobimodulation and thermal heating of MSC occur simultaneously. This combined laser treatment allows increasing the number of colonies by 6 times in comparison with the control and by more than 3 times in comparison with thermal heating alone. The mechanism of such an increase is associated with combined thermal and light effects of laser radiation of moderate intensity, which stimulates cell proliferation. This phenomenon can be used as the basis for solving the most important task of cell transplantation, associated with the expansion of autologous stem cells and activation of their proliferative potential.
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页码：523 / 526
页数：3
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