Necrobiotic xanthogranuloma successfully treated with autologous stem cell transplantation

被引：0

作者：

Jeroen S. Goede

Benjamin Misselwitz

Christian Taverna

Urs Schanz

Angela Dispenzieri

Yvonne Hummel

Ralph M. Trüeb

Jörg Fehr

机构：

[1] University Hospital Zürich,Clinic of Hematology

[2] Kantonsspital Münsterlingen,Clinic for Internal Medicine

[3] Mayo Clinic,Division of Hematology

[4] City Hospital Triemli,Clinic for Oncology and Hematology

[5] University Hospital Zürich,Department of Dermatology

来源：

Annals of Hematology | 2007年 / 86卷

关键词：

Paraprotein; Necrobiotic xanthogranuloma; Hematopoietic stem cell transplantation; Autologous transplantation; Blindness;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Paraproteinemia can be complicated by necrobiotic xanthogranuloma. Therapeutic options for this progressive disease are limited, and there is no agreement on a single best strategy. We report the case of a patient with a massive periorbital infiltration narrowing the palpebral fissure and blinding the patient. Conventional myeloma therapy had only limited benefit in our patient. However, he was successfully treated with high-dose chemotherapy followed by autologous stem cell transplantation, rendering the patient free of symptoms. This is the first report of autologous stem cell transplantation in a patient with necrobiotic xanthogranuloma.

引用

页码：303 / 306

页数：3

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