Necrobiotic xanthogranuloma successfully treated with autologous stem cell transplantation

被引：0
|
作者：
Jeroen S. Goede
Benjamin Misselwitz
Christian Taverna
Urs Schanz
Angela Dispenzieri
Yvonne Hummel
Ralph M. Trüeb
Jörg Fehr
机构：
[1] University Hospital Zürich,Clinic of Hematology
[2] Kantonsspital Münsterlingen,Clinic for Internal Medicine
[3] Mayo Clinic,Division of Hematology
[4] City Hospital Triemli,Clinic for Oncology and Hematology
[5] University Hospital Zürich,Department of Dermatology
来源：
Annals of Hematology | 2007年 / 86卷
关键词：
Paraprotein; Necrobiotic xanthogranuloma; Hematopoietic stem cell transplantation; Autologous transplantation; Blindness;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Paraproteinemia can be complicated by necrobiotic xanthogranuloma. Therapeutic options for this progressive disease are limited, and there is no agreement on a single best strategy. We report the case of a patient with a massive periorbital infiltration narrowing the palpebral fissure and blinding the patient. Conventional myeloma therapy had only limited benefit in our patient. However, he was successfully treated with high-dose chemotherapy followed by autologous stem cell transplantation, rendering the patient free of symptoms. This is the first report of autologous stem cell transplantation in a patient with necrobiotic xanthogranuloma.
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页码：303 / 306
页数：3
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