Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity

被引：0
作者：
Haiqin Jiang
Chuang-Wei Wang
Zhaoxi Wang
Yufei Dai
Yanping Zhu
Yun-Shien Lee
Yang Cao
Wen-Hung Chung
Songying Ouyang
Hongsheng Wang
机构：
[1] Chinese Academy of Medical Sciences & Peking Union Medical College,Department of Mycobacterium, Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology & Hospital for Skin Diseases
[2] Nanjing Medical University,Centre for Global Health, School of Public Health
[3] Chang Gung Memorial Hospital,Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Cancer Vaccine and Immune Cell Therapy Core Laboratory
[4] Chang Gung Memorial Hospital and Chang Gung University,Chang Gung Immunology Consortium
[5] Xiamen Chang Gung Hospital,Department of Dermatology
[6] Fujian Normal University,The Key Laboratory of Innate Immune Biology of Fujian Province, Biomedical Research Center of South China, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, College of Life Sciences
[7] Chinese Center for Disease Control and Prevention,National Institute of Occupational Health and Poison Control
[8] Chinese Academy of Sciences,National Laboratory of BiomacromoleculesInstitute of Biophysics
[9] Ming Chuan University,Department of Biotechnology
[10] Sichuan University,College of Life Sciences
[11] Chang Gung University,College of Medicine
[12] Chang Gung Memorial Hospital,Immune
[13] Tsinghua University,Oncology Center of Excellence
[14] Shanghai Jiao Tong University,Department of Dermatology, Beijing Tsinghua Chang Gung Hospital, School of Clinical Medicine
[15] Chang Gung Memorial Hospital,School of Medicine
来源：
Journal of Biomedical Science | / 29卷
关键词：
Dapsone; Dapsone-induced hypersensitivity syndrome; HLA-B*13:01; T-cell receptor;
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[1]  
Duong TA(2017)Severe cutaneous adverse reactions to drugs Lancet 390 1996-2011
[2]  
Valeyrie-Allanore L(2011)The DRESS syndrome: a literature review Am J Med 124 588-597
[3]  
Wolkenstein P(2002)Pathogenesis of drug-induced exanthems Allergy 57 884-893
[4]  
Cacoub P(2001)Hypersensitivity reactions during therapy with the nucleoside reverse transcriptase inhibitor abacavir Clin Ther 23 1603-1614
[5]  
Musette P(2008)Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity Immunity 28 822-832
[6]  
Descamps V(2004)Medical genetics: a marker for Stevens-Johnson syndrome Nature 428 486-4139
[7]  
Pichler W(2005)HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol Proc Natl Acad Sci U S A 102 4134-1065
[8]  
Yawalkar N(2015)Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction J Allergy Clin Immunol 135 1063-1569
[9]  
Schmid S(2012)Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome J Allergy Clin Immunol 129 1562-234
[10]  
Hetherington S(2015)Evolving models of the immunopathogenesis of T cell-mediated drug allergy: the role of host, pathogens, and drug response J Allergy Clin Immunol 136 219-1817
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