Psycho-social well-being and general health status after surgical treatment for localized renal cell carcinoma

被引：25

作者：

Ficarra V. ^{[1
]}

Novella G. ^{[1
]}

Sarti A. ^{[1
]}

Novara G. ^{[1
]}

Galfano A. ^{[1
]}

Cavalleri S. ^{[1
]}

Artibani W. ^{[1
]}

机构：

[1] Department of Urology, University of Verona, Verona

来源：

International Urology and Nephrology | 2002年 / 34卷 / 4期

关键词：

Nephron-sparing surgery; Quality of life; Radical nephrectomy; Renal cell carcinoma;

D O I：

10.1023/A:1025683306449

中图分类号：

学科分类号：

摘要：

Objective: To comparatively assess the psychological, social well-being and general state of health in patients with stage 1 renal cell carcinoma (RCC) (according to 1997 TNM), who underwent either elective nephron sparing surgery (NSS) or radical nephrectomy. Patients and methods: We evaluated the health-related quality of life (HR-QoL) in 88 patients who underwent radical nephrectomy and in 56 treated with elective NSS. The measurement of the main QoL components has been made using domain-specific questionnaires tested and validated in Italian language. Each questionnaire has been self-administrated during follow-up (cross-sectional study). Results: The two analysed group resulted perfectly comparable regarding age, gender, civil status, educational level, profession and mean follow-up. A low level anxiety has been documented in 11.4% of patients after radical nephrectomy and in 1.8% of those treated with an elective conservative surgery. The mean score difference between the two groups resulted statistically significant (p = 0.003). A mild depression has been recorded in 7% of patients who underwent radical nephrectomy and in 2.3% of NSS group. The mean score difference between the two groups was statistically significant (p = 0.01). The general health status was impaired in 12.5% of cases after radical nephrectomy and in 7% after elective NSS. Social problems were present in 18% of patients who underwent radical nephrectomy and in 18% of NSS group. There was no significant difference between radical and conservative group in terms of both General health Questionnaire and Social Problem Questionnaire mean scores. Conclusion: HR-QoL in patients who underwent surgery for RCC is not particularly negatively affected. Nevertheless, the comparative analysis of the results showed that, at a long term follow-up, radical surgery seems to eventually cause a more relevant negative impact on the psychological well-being than conservative surgery.

引用

页码：441 / 446

页数：5

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