Classic Kaposi’s sarcoma - complete response to radiation therapy: a case report

被引：0
作者：
Ramírez K. [1 ]
Zavala J. [1 ]
Morán D. [2 ]
Hernández D. [1 ]
Jiménez A. [1 ]
机构：
[1] Departments of Radiation Oncology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, Campeche
[2] Departments of Pathology, State Oncology Center, Avenida Lázaro Cárdenas número 208, esquina antiguo camino a Chiná, sector Las Flores. Código Postal, Campeche
来源：
Journal of Medical Case Reports | / 10卷 / 1期
关键词：
Case report; Classic Kaposi’s sarcoma; Kaposi’s sarcoma; Palliative radiotherapy in classic Kaposi’s sarcoma;
D O I：
10.1186/s13256-016-1101-6
中图分类号：
学科分类号：
摘要：
Background: Classic Kaposi’s sarcoma is a lymphatic endothelial cell neoplasm usually present on the skin of the upper and lower extremities. Although it commonly affects human immunodeficiency virus positive patients, there have been some human immunodeficiency virus negative cases reported. We report an uncommon presentation of stage IV classic Kaposi’s sarcoma in an human immunodeficiency virus negative patient in Latin America with complete clinical response using only radiation therapy treatment. Case presentation: A 78-year-old Mexican man with no evidence of human immunodeficiency virus infection presented with a painful widespread dermatosis with maculopapular, nodular, violaceous lesions on his legs and ulcerated lesions on his feet. A biopsy confirmed the lesions as classic Kaposi’s sarcoma. Radiotherapy treatment was delivered, prescribing a total dose of 30 Gy in 15 fractions with a complete clinical response within 15 months of follow-up. Conclusions: This is an unusual case since it is uncommon to use radiation therapy as the single treatment in stage IV classic Kaposi’s sarcoma; the efficacy of the treatment is shown in the impact in our patient’s recurrence-free survival, local control, and palliation of our patient’s symptoms. © 2016 The Author(s).
引用
收藏
页码：1 / 4
页数：3
相关论文
共 11 条
  • [1] Szajerka T., Jablecki J., Kaposi’s sarcoma revisited, AIDS Rev., 9, pp. 230-236, (2007)
  • [2] Sullivan R.J., Pantanowitz L., Casper C., Stebbing J., Dezube B.J., HIV/AIDS: epidemiology, pathophysiology, and treatment of Kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease, Clin Infect Dis, 47, 9, pp. 1209-1215, (2008)
  • [3] Antman K., Chang Y., Medical progress: Kaposi’s sarcoma, N Engl J Med., 342, pp. 1027-1038, (2000)
  • [4] Rojo D.E., Armando: Acta Medica Grupo Angeles, Sarcoma de Kaposi, 1, (2013)
  • [5] Iscovich J., Boffetta P., Winkelmann R., Brennan P., Classic Kaposi’s sarcoma as a second primary neoplasm, Int J Cancer., 80, pp. 178-182, (1999)
  • [6] Brambilla L., Boneschi V., Taglioni M., Ferrucci S., Staging of classic Kaposi’s sarcoma: a useful tool for therapeutic choices, Eur J Dermatol, 13, 1, pp. 83-86, (2003)
  • [7] Cooper J.S., Steinfeld A.D., Lerch I., Intentions and outcomes in the radiotherapeutic management of epidemic Kaposi’s sarcoma, Int J Radiat Oncol Biol Phys, 20, 3, pp. 419-422, (1991)
  • [8] Akmansu M., Goksel F., Erpolat O.P., Unsal D., Karahacioglu E., Bora H., The palliative radiotherapy of classic Kaposi’s sarcoma of foot region: retrospective evaluation, Int J Hematol Oncol., 24, pp. 147-152, (2014)
  • [9] Nicolini G., Abraham S., Fogliata A., Jordaan A., Clivio A., Vanetti E., Cozzi L., Critical appraisal of volumetric-modulated arc therapy compared with electrons for the radiotherapy of cutaneous Kaposi’s sarcoma of lower extremities with bone sparing, Br J Radiol., 86, (2013)
  • [10] Singh N.B., Lakier R.H., Donde B., Hypofractionated radiation therapy in the treatment of epidemic Kaposi sarcoma--a prospective randomized trial, Radiother Oncol, 88, 2, pp. 211-216, (2008)
12