Off-label intravenous thrombolysis for early recurrent brain embolism associated with aortic arch thrombus

被引:0
作者
Ioanna Koutroulou
Georgios Tsivgoulis
Vasileios Rafailidis
Elissavet Psoma
Konstantinos Kouskouras
Panagiotis Fotiadis
Nikolaos Grigoriadis
Theodoros Karapanayiotides
机构
[1] Aristotle University of Thessaloniki,Second Department of Neurology
[2] School of Medicine,Second Department of Neurology
[3] Faculty of Health Sciences,Department of Neurology
[4] AHEPA University Hospital,Department of Radiology
[5] National & Kapodistrian University of Athens,undefined
[6] “Attikon” University Hospital,undefined
[7] University of Tennessee Health Science Center,undefined
[8] Aristotle University of Thessaloniki,undefined
[9] School of Medicine,undefined
[10] Faculty of Health Sciences,undefined
[11] AHEPA University Hospital,undefined
来源
Neurological Research and Practice | / 3卷
关键词
Off-label thrombolysis; Aortic arch thrombus; Stroke; Brain embolism;
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摘要
Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent major infarction 5 days after a minor left MCA territory stroke. She had a floating aortic arch thrombus and she was treated safely and effectively with off-label IVT. Patients with small infarct volumes and mild/no residual neurological deficits after an initial stroke might be considered for IVT in case of early recurrence. IVT may be reasonable in a context of acute severely disabling stroke associated with aortic arch thrombus.
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