Is there no need to discuss adjuvant chemotherapy in stage II colon cancer patients with high tumor budding and lymphovascular invasion?

[1] Bilchik AJ(2002)The use of molecular profiling of early colorectal cancer to predict micrometastases Arch Surg 137 1377-1383

[2] Nora DT(2018)Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer Int J Clin Oncol 23 1-34

[3] Saha S(2013)Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer Hum Pathol 44 697-705

[4] Watanabe T(2006)Should adjuvant chemotherapy become standard treatment for patients with stage II colon cancer? For the proposal Lancet Oncol 7 515-516

[5] Muro K(2020)Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Ann Oncol 31 1291-1305

[6] Ajioka Y(2019)Treatment of patients with early-stage colorectal cancer: ASCO resource-stratified guideline J Glob Oncol 5 1-19

[7] Horcic M(2021)Colon cancer, version 2.2021, NCCN Clinical Practice Guidelines in Oncology J Natl Compr Canc Netw 19 329-359

[8] Koelzer VH(2017)Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 Mod Pathol 30 1299-1311

[9] Karamitopoulou E(1993)Prognostic value of tumor “budding” in patients with colorectal cancer Dis Colon Rectum 36 627-635

[10] Terracciano L(2002)Tumour ‘budding’ as an index to estimate the potential of aggressiveness in rectal cancer Histopathology 40 127-132

[1] Bilchik AJ(2002)The use of molecular profiling of early colorectal cancer to predict micrometastases Arch Surg 137 1377-1383

[2] Nora DT(2018)Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2016 for the treatment of colorectal cancer Int J Clin Oncol 23 1-34

[3] Saha S(2013)Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer Hum Pathol 44 697-705

[4] Watanabe T(2006)Should adjuvant chemotherapy become standard treatment for patients with stage II colon cancer? For the proposal Lancet Oncol 7 515-516

[5] Muro K(2020)Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up Ann Oncol 31 1291-1305

[6] Ajioka Y(2019)Treatment of patients with early-stage colorectal cancer: ASCO resource-stratified guideline J Glob Oncol 5 1-19

[7] Horcic M(2021)Colon cancer, version 2.2021, NCCN Clinical Practice Guidelines in Oncology J Natl Compr Canc Netw 19 329-359

[8] Koelzer VH(2017)Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 Mod Pathol 30 1299-1311

[9] Karamitopoulou E(1993)Prognostic value of tumor “budding” in patients with colorectal cancer Dis Colon Rectum 36 627-635

[10] Terracciano L(2002)Tumour ‘budding’ as an index to estimate the potential of aggressiveness in rectal cancer Histopathology 40 127-132