Male infertility

被引：0

作者：

Michael L. Eisenberg

Sandro C. Esteves

Dolores J. Lamb

James M. Hotaling

Aleksander Giwercman

Kathleen Hwang

Yu-Sheng Cheng

机构：

[1] Stanford University School of Medicine,Department of Urology

[2] Stanford University School of Medicine,Department of Obstetrics & Gynecology

[3] ANDROFERT Andrology and Human Reproduction Clinic,Division of Urology, Department of Surgery, Faculty of Medical Sciences

[4] State University of Campinas (UNICAMP),Center for Reproductive Genomics

[5] Weill Cornell Medical College,Englander Institute for Precision Medicine

[6] Weill Cornell Medical College,Department of Urology

[7] Weill Cornell Medical College,Division of Urology, Department of Surgery

[8] University of Utah School of Medicine,Department of Translational Medicine

[9] Lund University,Department of Urology, National Cheng Kung University Hospital, College of Medicine

[10] University of Pittsburgh Medical Center,undefined

[11] National Cheng Kung University,undefined

来源：

Nature Reviews Disease Primers | / 9卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Clinical infertility is the inability of a couple to conceive after 12 months of trying. Male factors are estimated to contribute to 30–50% of cases of infertility. Infertility or reduced fertility can result from testicular dysfunction, endocrinopathies, lifestyle factors (such as tobacco and obesity), congenital anatomical factors, gonadotoxic exposures and ageing, among others. The evaluation of male infertility includes detailed history taking, focused physical examination and selective laboratory testing, including semen analysis. Treatments include lifestyle optimization, empirical or targeted medical therapy as well as surgical therapies that lead to measurable improvement in fertility. Although male infertility is recognized as a disease with effects on quality of life for both members of the infertile couple, fewer data exist on specific quantification and impact compared with other health-related conditions.

引用

共 810 条

[1]

Schlegel PN(2021)Fertility evaluation of infertile women: a committee opinion Fertil. Steril. 116 1255-1265

[2]

Thonneau P(2021)Diagnosis and treatment of infertility in men: AUA/ASRM guideline part I Fertil. Steril. 115 54-61

[3]

Agarwal A(1991)Incidence and main causes of infertility in a resident population (1,850,000) of three French regions (1988–1989) Hum. Reprod. 6 811-816

[4]

Mulgund A(2015)A unique view on male infertility around the globe Reprod. Biol. Endocrinol. 13 657-662

[5]

Hamada A(2019)Reproductive endocrinologists are the gatekeepers for male infertility care in North America: results of a North American survey on the referral patterns and characteristics of men presenting to male infertility specialists for infertility investigations Fertil. Steril. 112 1030-1034

[6]

Chyatte MR(2013)Frequency of the male infertility evaluation: data from the national survey of family growth J. Urol. 189 1172-1177

[7]

Samplaski MK(1998)Relation between semen quality and fertility: a population-based study of 430 first-pregnancy planners Lancet 352 145-153

[8]

Eisenberg ML(2000)Semen quality and human fertility: a prospective study with healthy couples J. Androl. 21 1388-1393

[9]

Lathi RB(2001)Sperm morphology, motility, and concentration in fertile and infertile men N. Engl. J. Med. 345 453-462

[10]

Baker VL(2014)Semen quality and time to pregnancy: the Longitudinal Investigation of Fertility and the Environment Study Fertil. Steril. 101 499-507

← 1 2 3 4 5 6 7 8 9 10 →