Novel thiol- and thioether-containing amino acids: cystathionine and homocysteine families

被引：0
作者：
Luigi Longobardo
Nunzia Cecere
Marina DellaGreca
Ivan de Paola
机构：
[1] Università degli Studi di Napoli Federico II,Dipartimento di Scienze Chimiche
[2] Università degli Studi di Napoli Federico II,Dipartimento delle Scienze Biologiche
来源：
Amino Acids | 2013年 / 44卷
关键词：
Cystathionine; Homocysteine; Cysteine thioalkylation; Bis-amino acids; Unnatural amino acids;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Natural l-homocysteine and l,l-cystathionine, along with a series of unnatural analogues, have been prepared from l-aspartic and l-glutamic acid. Manipulation of the protected derivatives provided ω-iodoamino acids, which were used in thioalkylation reactions of sulfur nucleophiles, such as the ester of l-cysteine and potassium thioacetate.
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页码：443 / 448
页数：5
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