Zebrafish as a model for leukemia and other hematopoietic disorders

被引：0
作者：
Parisa Rasighaemi
Faiza Basheer
Clifford Liongue
Alister C Ward
机构：
[1] School of Medicine,
[2] Deakin University,undefined
[3] Centre for Molecular and Medical Research,undefined
[4] Deakin University,undefined
来源：
Journal of Hematology & Oncology | / 8卷
关键词：
Zebrafish; Leukemia; Myeloproliferative disorder; Myelodysplastic syndrome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Zebrafish is an established model for the study of vertebrate development, and is especially amenable for investigating hematopoiesis, where there is strong conservation of key lineages, genes, and developmental processes with humans. Over recent years, zebrafish has been increasingly utilized as a model for a range of human hematopoietic diseases, including malignancies. This review provides an overview of zebrafish hematopoiesis and describes its application as a model of leukemia and other hematopoietic disorders.
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