Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

被引：0
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作者：
Joshua E Allen
Gabriel Krigsfeld
Luv Patel
Patrick A Mayes
David T Dicker
Gen Sheng Wu
Wafik S El-Deiry
机构：
[1] University of Pennsylvania School of Medicine,Departments of Medicine, Genetics, and Pharmacology, Laboratory of Molecular Oncology and Cell Cycle Regulation
[2] Current affiliation: Oncoceutics,Department of Medical Oncology and Molecular Therapeutics Program
[3] Inc.,Department of Pathology
[4] Laboratory of Translational Oncology and Experimental Cancer Therapeutics,undefined
[5] Fox Chase Cancer Center,undefined
[6] Program in Molecular Biology and Genetics,undefined
[7] Karmanos Cancer Institute,undefined
[8] Wayne State University School of Medicine,undefined
来源：
Molecular Cancer | / 14卷
关键词：
ONC201; TIC10; TRAIL; TRAIL-inducing compound; TNF-related apoptosis-inducing ligand; DR5; Foxo3a; Gene regulation;
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