Perivascular epithelial cell tumor (PEComa) of the pancreas: a case report and review of previous literatures

被引：0
作者：
Yusuke Mizuuchi
Kazuyoshi Nishihara
Akifumi Hayashi
Sadafumi Tamiya
Satoshi Toyoshima
Yoshinao Oda
Toru Nakano
机构：
[1] Kitakyushu Municipal Medical Center,Department of Surgery
[2] Kitakyushu Municipal Medical Center,Department of Pathology
[3] JR Kyushu Hospital,Department of Surgery
[4] Kyushu University,Department of Anatomical Pathology, Graduate School of Medical Sciences
来源：
Surgical Case Reports | / 2卷 / 1期
关键词：
Perivascular epithelioid cell tumor; Pancreatic neoplasm; HMB-45; Alpha-smooth muscle actin;
D O I：
10.1186/s40792-016-0186-x
中图分类号：
学科分类号：
摘要：
Perivascular epithelial cell tumors (PEComas), firstly described by Bonetti in 1992, are a family of mesenchymal tumor composed of perivascular epithelioid cells having epithelioid or spindle morphology and exhibiting melanocytic and myogenic immunoreactivities. We herein described a 61-year-old woman who presented with epigastric pain. Preoperative imaging studies showed that 7-cm-sized mass was located in pancreatic head and body, and pancreaticoduodenectomy was performed. Histological findings showed that the tumor was composed of clear epithelioid cells with abundant glycogen granules, which grew in a nested and alveolar pattern around blood vessels. The tumor cells showed immunoreactivities for HMB-45 but did not express epithelial or endocrine markers. These histological features indicated those of PEComa. This report underlines that we should recognize PEComa as a preoperative differential diagnosis of pancreatic tumors.
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