Obesity and type 2 diabetes

被引:17
作者
Toplak, Hermann [1 ]
Hoppichler, Friedrich [2 ]
Wascher, Thomas C. [5 ]
Schindler, Karin [3 ]
Ludvik, Bernhard [4 ]
机构
[1] Med Univ Graz, Univ Klin Innere Med, Graz, Austria
[2] Krankenhaus Barmherzigen Bruder, Innere Med Abt, Salzburg, Austria
[3] Med Univ Wien, Klin Abt Innere Med 3, Vienna, Austria
[4] Krankenanstalt Rudolfstiftung Stadt Wien, Innere Med Abt, Vienna, Austria
[5] Hanuschkrankenhaus, Med Abt 1, Vienna, Austria
关键词
Obesity; Typ; 2; diabetes; EASO POSITION STATEMENT; WEIGHT-LOSS; LOW-CARBOHYDRATE; RISK; MANAGEMENT; OVERWEIGHT; STRENGTH; DIETS; MASS;
D O I
10.1007/s00508-016-0986-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity and Type 2 Diabetes are nowadays summarized as "diabesity". That is due to the fact that obesity is frequently preceding and the most important risk factor in the increase of Type 2 Diabetes. The body mass index (BMI) is a crude measure of body fatness. Even normal weight persons can have lack in muscles (sarcopenia), which leads to the recommendation to measure waist und body fatness (e.g. BIA). Lifestyle management including nutrition and physical activity are important for diabetes prevention. In the therapy of Type 2 Diabetes body weight is increasingly used as secondary target. Also the choice of the anti-diabetic medication and concomitant medications is increasingly influenced by body weight. The significance of anti-obesity medications in the therapy of type 2 diabetes will have to be clarified by future studies. Bariatric surgery is at present indicated with a BMI above BMI > 35 kg/m(2) and can lead at least to partial diabetes remission but has to be part of a lifelong care concept.
引用
收藏
页码:S196 / S200
页数:5
相关论文
共 33 条
[11]   Body mass index classification misses subjects with increased cardiometabolic risk factors related to elevated adiposity [J].
Gomez-Ambrosi, J. ;
Silva, C. ;
Galofre, J. C. ;
Escalada, J. ;
Santos, S. ;
Millan, D. ;
Vila, N. ;
Ibanez, P. ;
Gil, M. J. ;
Valenti, V. ;
Rotellar, F. ;
Ramirez, B. ;
Salvador, J. ;
Fruehbeck, G. .
INTERNATIONAL JOURNAL OF OBESITY, 2012, 36 (02) :286-294
[12]   Global Obesity Study on Drivers for Weight Reduction Strategies [J].
Grebitus, Carola ;
Hartmann, Monika ;
Reynolds, Nikolai .
OBESITY FACTS, 2015, 8 (01) :77-86
[13]   Fat or Fit: What Is More Important? [J].
Hainer, Vojtech ;
Toplak, Hermann ;
Stich, Vladimir .
DIABETES CARE, 2009, 32 :S392-S397
[14]   Obesity and diabetes in the developing world - A growing challenge [J].
Hossain, Parvez ;
Kawar, Bisher ;
Nahas, Meguid El .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (03) :213-215
[15]   Global burden of obesity in 2005 and projections to 2030 [J].
Kelly, T. ;
Yang, W. ;
Chen, C-S ;
Reynolds, K. ;
He, J. .
INTERNATIONAL JOURNAL OF OBESITY, 2008, 32 (09) :1431-1437
[16]   Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin [J].
Knowler, WC ;
Barrett-Connor, E ;
Fowler, SE ;
Hamman, RF ;
Lachin, JM ;
Walker, EA ;
Nathan, DM .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (06) :393-403
[17]   The Diabetes Excess Weight Loss (DEWL) Trial: a randomised controlled trial of high-protein versus high-carbohydrate diets over 2 years in type 2 diabetes [J].
Krebs, J. D. ;
Elley, C. R. ;
Parry-Strong, A. ;
Lunt, H. ;
Drury, P. L. ;
Bell, D. A. ;
Robinson, E. ;
Moyes, S. A. ;
Mann, J. I. .
DIABETOLOGIA, 2012, 55 (04) :905-914
[18]   The effect of high-protein, low-carbohydrate diets in the treatment of type 2 diabetes: a 12 month randomised controlled trial [J].
Larsen, R. N. ;
Mann, N. J. ;
Maclean, E. ;
Shaw, J. E. .
DIABETOLOGIA, 2011, 54 (04) :731-740
[19]   OBESITY, WEIGHT-LOSS AND PROGNOSIS IN TYPE-2 DIABETES [J].
LEAN, MEJ ;
POWRIE, JK ;
ANDERSON, AS ;
GARTHWAITE, PH .
DIABETIC MEDICINE, 1990, 7 (03) :228-233
[20]   Prevalence and outcomes of comorbid metabolic and cardiovascular conditions in middle- and older-age adults [J].
Oldridge, NB ;
Stump, TE ;
Nothwehr, FK ;
Clark, DO .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2001, 54 (09) :928-934