Immobilization effects in young and older adults

被引:0
作者
M. L. Urso
P. M. Clarkson
T. B. Price
机构
[1] University of Massachusetts,Department of Exercise Science
[2] Yale School of Medicine,undefined
来源
European Journal of Applied Physiology | 2006年 / 96卷
关键词
Aging; Atrophy; Immobilization;
D O I
暂无
中图分类号
学科分类号
摘要
This experiment compared the effects of disuse on the adductor pollicis (AP) muscle in young (YM) and old (OM) men. The AP of the YM and OM was assessed for strength (MVC), compound muscle action potential (CMAP), and volume, and then immobilized for 2 weeks. MVC decreased ~22% in the YM, and OM (P<0.001). AP volume was 4.1% (not significant) and 9.5% (P<0.05) less in the YM and OM, respectively. CMAP increased in the OM 0, 24, and 48 h post-immobilization, and did not change in the YM. However, the YM showed a greater decrease in specific force as compared to the OM. YM and OM experienced similar losses in strength, yet muscle volume loss was only significant in OM. Although OM are more susceptible to immediate losses in muscle volume, muscle activation strategies appear to preserve strength during atrophy.
引用
收藏
页码:564 / 571
页数:7
相关论文
共 64 条
[1]  
Ansved T(1995)Effects of immobilization on the rat soleus muscle in relation to age Acta Physiol Scand 154 291-302
[2]  
Brooks SV(1994)Skeletal muscle weakness in old age: underlying mechanisms Med Sci Sports Exerc 26 432-439
[3]  
Faulkner JA(1996)Differential effects of reduced muscle use (hindlimb unweighting) on skeletal muscle with aging Aging 8 99-105
[4]  
Brown M(2001)Skeletal muscle disuse induces fibre type-dependent enhancement of Na(+) channel expression Brain 124 1100-1113
[5]  
Hasser EM(2003)Age-related differences in synaptic plasticity following muscle unloading J Neurobiol 57 246-256
[6]  
Desaphy JF(2005)Temperature dependence of soleus H-reflex and M wave in young and older women Eur J Appl Physiol 94 491-499
[7]  
Pierno S(1987)Electrical and mechanical changes in immobilized human muscle J Appl Physiol 62 2168-2173
[8]  
Leoty C(1990)Effects of immobilization on contractile properties, recruitment and firing rates of human motor units J Physiol 422 55-65
[9]  
George AL(2000)Skeletal muscle fiber quality in older men and women Am J Physiol Cell Physiol 279 C611-C618
[10]  
De Luca A(1993)Impairment of neuromuscular propagation during human fatiguing contractions at submaximal forces J Physiol 460 549-572