Prognostic value of phosphorylated Raf kinase inhibitory protein at serine 153 and its predictive effect on the clinical response to radiotherapy in nasopharyngeal carcinoma

被引:0
作者
Siwei Li
Taowen Liu
Wenfa Mo
Qiaoyan Hou
Yingqiong Zhou
Meilian Liu
Zhoukai He
Zhengchun Liu
Qiuqiu Chen
Hua Wang
Xiang Guo
Weixiong Xia
Musheng Zeng
Haiyun Zhao
机构
[1] The Affiliated Hospital of Guilin Medical University,Department of Radiation Oncology
[2] Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Department of Oncology
[3] The Affiliated Hospital of Guilin Medical University,Department of Pathology
[4] Head and Neck Surgery,Department of Otorhinolaryngology
[5] The Affiliated Hospital of Guilin Medical University,State Key Laboratory of Oncology in Southern China
[6] Collaborative Innovation Center for Cancer Medicine,Department of Nasopharyngeal Carcinoma
[7] Sun Yat-sen University Cancer Center,Department of Otorhinolaryngology
[8] State Key Laboratory of Oncology in Southern China,undefined
[9] Head and Neck Surgery,undefined
[10] Nanxishan Hospital of Guangxi Zhuang Autonomous Region,undefined
来源
Radiation Oncology | / 11卷
关键词
Phosphorylated Raf kinase inhibitor protein (pRKIP); Nasopharyngeal carcinoma; Radiotherapy; Sensitivity; Prediction; Prognosis;
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[1]  
Zeng L(2014)Intensity-modulated radiotherapy for stage IVA/IVB nasopharyngeal carcinoma: clinical outcomes and patterns of failure in an endemic area in China Strahlenther Onkol. 190 993-1000
[2]  
Tian YM(2008)Loss of Raf kinase inhibitory protein induces radioresistance in prostate cancer Int J Radiat Oncol Biol Phys. 72 153-60
[3]  
Sun XM(2010)Raf kinase inhibitor protein correlates with sensitivity of nasopharyngeal carcinoma to radiotherapy J Cell Biochem. 110 975-81
[4]  
Huang Y(2004)RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis J Biol Chem. 279 17515-23
[5]  
Chen CY(2009)The activated NF-kappaB-Snail-RKIP circuitry in cancer regulates both the metastatic cascade and resistance to apoptosis by cytotoxic drugs Crit Rev Immunol. 29 241-54
[6]  
Han F(2007)Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation J Immunol. 179 5441-53
[7]  
Woods Ignatoski KM(2006)Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer The Prostate. 66 248-56
[8]  
Grewal NK(2006)Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients J Clin Oncol 24 5672-9
[9]  
Markwart SM(2012)Prognostic value of RKIP and p-ERK in gastric cancer J Exp Clin Cancer Res. 31 30-7
[10]  
Vellaichamy A(2007)Loss of raf-1 kinase inhibitor protein expression is associated with tumor progression and metastasis in colorectal cancer Am J Clin Pathol. 127 820-91