Unusual presentation of giant cell tumor originating from a facet joint of the thoracic spine in a child: A case report and review of the literature

被引：5

作者：

Siribumrungwong K. ^{[1
]}

Tangtrakulwanich B. ^{[2
]}

Nitiruangjaras A. ^{[3
]}

机构：

[1] Department of Orthopedic Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai

[2] Department of Orthopedic Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai

[3] Department of Pathology, Faculty of Medicine, Prince of Songkla University, Hat Yai

来源：

Journal of Medical Case Reports | / 7卷 / 1期

关键词：

Giant cell tumor; Spine; Synovium;

D O I：

10.1186/1752-1947-7-178

中图分类号：

学科分类号：

摘要：

Introduction. Giant cell tumor of the synovium is a common benign lesion that frequently occurs at the tendon sheaths in the hand; it is usually found in adults over 30 years old. It is related to pigmented villonodular synovitis. Giant cell tumor of the synovium or pigmented villonodular synovitis has been described rarely in the axial skeleton especially in the thoracic vertebrae of a child. Case presentation. A previously healthy 7-year-old Thai girl presented with back pain and progressive paraparesis and was unable to walk for 1 month. She had weakness and hyperreflexia of both lower extremities. Magnetic resonance imaging showed a well-defined homogeneously and intensely enhanced extradural mass with cord compression at T4 to T7 levels. The patient underwent laminectomy at T4 through to T7 and total tumor removal. Permanent histopathologic sections and immunostains revealed a giant cell tumor of the synovium. Postoperative neurological status recovered to grade V. Magnetic resonance imaging at the 1-year follow-up showed no recurrence and there was no clinical recurrence at the 2-year follow-up. Conclusion: We report an extremely rare case of giant cell tumor in the epidural space that extended from a thoracic facet joint. The tumor was removed successfully through laminectomies. Although giant cell tumor of a facet joint of the thoracic spine is very rare, it must be considered in the differential diagnosis for masses occurring in the epidural space in a child. Total tumor removal is the best treatment. Careful monitoring of recurrence can achieve a good clinical outcome. © 2013 Siribumrungwong et al.; licensee BioMed Central Ltd.

引用

共 15 条

[1]

De St. Aubain Somerhausen N., Dal Cin P., Giant cell tumour of tendon sheath, Pathology and Genetics of Tumours of Soft Tissue and Bone, pp. 110-111, (2001)

[2]

Enginger F.M., Weiss S.W., Benign tumors and tumor-like lesions of synovial tissue, Soft Tissue Tumors, pp. 638-658, (1988)

[3]

Ushijima M., Hashimoto H., Tsuneyoshi M., Enjoji M., Giant cell tumor of the tendon sheath (nodular tenosynovitis). A study of 207 cases to compare the large joint group with the common digit group, Cancer, 57, 4, pp. 875-884, (1986)

[4]

Rubin B.P., Tenosynovial giant cell tumor and pigmented villonodular synovitis: A proposal for unification of these clinically distinct but histologically and genetically identical lesions, Skeletal Radiology, 36, 4, pp. 267-268, (2007)

[5]

Dingle S.R., Flynn Sr. J.C., Flynn Jr. J.C., Stewart G., Giant-cell tumor of the tendon sheath involving the cervical spine: A case report, Journal of Bone and Joint Surgery - Series A, 84, 9, pp. 1664-1667, (2002)

[6]

Giannini C., Scheithauer B.W., Wenger D.E., Unni K.K., Pigmented villonodular synovitis of the spine: A clinical, radiological, and morphological study of 12 cases, Journal of Neurosurgery, 84, 4, pp. 592-597, (1996)

[7]

Furlong M.A., Motamedi K., Laskin W.B., Vinh T.N., Murphey M., Sweet D.E., Fetsch J.F., Synovial-type giant cell tumors of the vertebral column: A clinicopathologic study of 15 cases, with a review of the literature and discussion of the differential diagnosis, Human Pathology, 34, 7, pp. 670-679, (2003)

[8]

Gupta R., Jambhekar N., Sanghvi D., Giant-cell tumour of the synovium in a facet joint in the thoracic spine of a child, Journal of Bone and Joint Surgery - Series B, 90, 2, pp. 236-239, (2008)

[9]

Clark L.J.P., McCormick P.W., Domenico D.R., Savory L., Pigmented villonodular synovitis of the spine. Case report, Journal of Neurosurgery, 79, 3, pp. 456-459, (1993)

[10]

Kuwabara H., Uda H., Nakashima H., Pigmented villonodular synovitis (giant cell tumor of the synovium) occurring in the vertebral column. Report of a case, Acta Pathol Jpn, 42, pp. 69-74, (1992)

← 1 2 →