Development of bone marrow lesions is associated with adverse effects on knee cartilage while resolution is associated with improvement - a potential target for prevention of knee osteoarthritis: a longitudinal study

[1] Sharma L(2001)The role of knee alignment in disease progression and functional decline in knee osteoarthritis JAMA 286 188-195

[2] Song J(2007)Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging Arthritis Rheum 56 2986-2992

[3] Felson DT(2000)Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings Radiology 215 835-840

[4] Cahue S(2001)The association of bone marrow lesions with pain in knee osteoarthritis Ann Intern Med 134 541-549

[5] Shamiyeh E(2003)MR imaging findings in different stages of disease and correlation with clinical findings Radiology 226 373-381

[6] Dunlop DD(2005)Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis Arthritis Rheum 52 2822-2829

[7] Felson DT(2006)Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis Arthritis Rheum 54 1529-1535

[8] Niu J(2007)A study of the prevalence and associations of subchondral bone marrow lesions in the knees of healthy middle-aged women Osteoarthritis Cartilage 15 1437-1442

[9] Guermazi A(2007)Association of bone marrow lesions with knee structures and risk factors for bone marrow lesions in the knees of clinically healthy, community-based adults Semin Arthritis Rheum 37 112-118

[10] Roemer F(2007)Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis: associations with clinical features Eur Radiol 17 3073-3078

[1] Sharma L(2001)The role of knee alignment in disease progression and functional decline in knee osteoarthritis JAMA 286 188-195

[2] Song J(2007)Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging Arthritis Rheum 56 2986-2992

[3] Felson DT(2000)Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings Radiology 215 835-840

[4] Cahue S(2001)The association of bone marrow lesions with pain in knee osteoarthritis Ann Intern Med 134 541-549

[5] Shamiyeh E(2003)MR imaging findings in different stages of disease and correlation with clinical findings Radiology 226 373-381

[6] Dunlop DD(2005)Bone marrow abnormalities on magnetic resonance imaging are associated with type II collagen degradation in knee osteoarthritis Arthritis Rheum 52 2822-2829

[7] Felson DT(2006)Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis Arthritis Rheum 54 1529-1535

[8] Niu J(2007)A study of the prevalence and associations of subchondral bone marrow lesions in the knees of healthy middle-aged women Osteoarthritis Cartilage 15 1437-1442

[9] Guermazi A(2007)Association of bone marrow lesions with knee structures and risk factors for bone marrow lesions in the knees of clinically healthy, community-based adults Semin Arthritis Rheum 37 112-118

[10] Roemer F(2007)Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis: associations with clinical features Eur Radiol 17 3073-3078