Atomoxetine accelerates attentional set shifting without affecting learning rate in the rat

被引:0
作者
Nelson K. Totah
Nikos K. Logothetis
Oxana Eschenko
机构
[1] Max Planck Institute for Biological Cybernetics,Department of Physiology of Cognitive Processes
来源
Psychopharmacology | 2015年 / 232卷
关键词
Attention; Learning; Set-shifting; Behavioral flexibility; Rat; Norepinephrine; Prefrontal cortex; ADHD; Schizophrenia;
D O I
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中图分类号
学科分类号
摘要
引用
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页码:3697 / 3707
页数:10
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[1]  
Aston-Jones G(2005)Adaptive gain and the role of the locus coeruleus-norepinephrine system in optimal performance J Comp Neurol 493 99-110
[2]  
Cohen JD(1994)Locus coeruleus neurons in monkey are selectively activated by attended cues in a vigilance task J Neurosci 14 4467-4480
[3]  
Aston-Jones G(2012)Atomoxetine modulates spontaneous and sensory-evoked discharge of locus coeruleus noradrenergic neurons Neuropharmacology 60 1111-1120
[4]  
Rajkowski J(2006)Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function Biol Psychiatry 99 262-274
[5]  
Kubiak P(2011)Cognitive enhancers for the treatment of ADHD Pharmacol Biochem Behav 20 4320-4324
[6]  
Alexinsky T(2000)Medial frontal cortex mediates perceptual attentional set shifting in the rat J Neurosci 20 791-802
[7]  
Bari A(2004)Reward expectation, orientation of attention and locus coeruleus-medial frontal cortex interplay during learning Eur J Neurosci 27 699-711
[8]  
Aston-Jones G(2002)Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat a potential mechanism for efficacy in attention deficit/hyperactivity disorder Neuropsychopharmacology 1 552-559
[9]  
Berridge CW(2011)Atomoxetine facilitates attentional set shifting in adolescent rats Dev Cogn Neurosci 55 1067-1070
[10]  
Devilbiss DM(1990)Blockade of the noradrenaline carrier increases extracellular dopamine concentrations in the prefrontal cortex: evidence that dopamine is taken up in vivo by noradrenergic terminals J Neurochem 64 782-788