New Sulfoalkylresorcinol from Marine-derived Fungus, Zygosporium sp. KNC52

被引：0
作者：
Kaneo Kanoh
Kyoko Adachi
Satoru Matsuda
Yoshikazu Shizuri
Ko Yasumoto
Takenori Kusumi
Kayo Okumura
Teruo Kirikae
机构：
[1] Marine Biotechnology Institute Co.,Department of Infectious Diseases
[2] Ltd.,Department of Microbiology and Immunology
[3] Graduate School of Pharmaceutical Sciences,undefined
[4] The University of Tokushima,undefined
[5] Research Institute,undefined
[6] International Medical Center of Japan,undefined
[7] Shimane University Faculty of Medicine,undefined
来源：
The Journal of Antibiotics | 2008年 / 61卷
关键词：
marine-derived fungus; sulfoalkylresorcinol; FtsZ;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new sulfoalkylresorcinol (1) was isolated from the marine-derived fungus, Zygosporium sp. KNC52. The structure of 1 was elucidated by spectroscopic methods including MS and NMR, and the absolute stereochemistry was determined by the modified Mosher's method. Compound 1 inhibited FtsZ polymerization in vitro and exhibited weak antimicrobial activity against multi-drugresistant bacteria.
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页码：192 / 194
页数：2
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