Relation between mercury concentrations in saliva, blood, and urine in subjects with amalgam restorations

被引：23

作者：

Ganss C. ^{[1
,6
]}

Gottwald B. ^{[2
]}

Traenckner I. ^{[3
]}

Kupfer J. ^{[2
]}

Eis D. ^{[4
]}

Mönch J. ^{[1
,6
]}

Gieler U. ^{[5
]}

Klimek J. ^{[1
,6
]}

机构：

[1] Department of Operative and Preventive Dentistry, Dental Clinic, Justus-Liebig-University, 35392 Giessen

[2] Department of Medical Psychology, Justus-Liebig-University, 35392 Giessen

[3] Centre of Dermatology and Andrology, Justus-Liebig-University, 35392 Giessen

[4] Robert Koch Institute Berlin, 12101 Berlin

[5] Centre of Psychosomatic Medicine, Justus-Liebig-University, 35392 Giessen

[6] Department of Operative and Preventive Dentistry, Dental Clinic, Justus-Liebig-University, 35392 Giessen

来源：

Clinical Oral Investigations | 2000年 / 4卷 / 4期

关键词：

Keywords Mercury; Amalgam; Saliva; Blood; Urine;

D O I：

10.1007/s007840000089

中图分类号：

学科分类号：

摘要：

The aim was to determine the relationship between mercury content of resting and stimulated saliva, and blood and urine. Eighty subjects participated; 40 of them attributed their self-reported complaints to dental amalgam (patients), the others were matched with respect to age, sex and amalgam restorations (controls). Serum, 24-h urine, resting and chewing stimulated saliva were analyzed for mercury using the ASS-technique. Quality, number, surfaces and total area of amalgam fillings were recorded clinically and using study models. Median (range) mercury levels in serum were 0.67 (0.1-1.52) microgram/l for patients and 0.60 (0.1-1.3) for controls. In urine levels were found to be 0.77 (0.11-5.16) and 0.94 (0.17-3.01) microgram/g creatinine respectively. No significant differences were found between the groups. Resting saliva contained 2.97 (0.10-45.46) micrograms/l in patients and 3.69 (0.34-55.41) in controls (not significant). Chewing mobilized an additional amount of 16.78 (-6.97 to 149.78) micrograms/l in patients and 49.49 (-1.36 to 504.63) in controls (P < or = 0.01). Only a weak correlation was found between mobilized mercury in saliva and serum (r = 0.27; P < or = 0.05) or urine (r = 0.47; P < or = 0.001). For resting saliva the respective values were r = 0.45 (P < or = 0.001) and r = 0.60 (P < or = 0.001). Saliva testing is not an appropriate measure for estimating the mercury burden derived from dental amalgam.

引用

页码：206 / 211

页数：5